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Novel insights into the disease transcriptome of human diabetic glomeruli and tubulointerstitium

BACKGROUND: Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, affecting ∼30% of the rapidly growing diabetic population, and strongly associated with cardiovascular risk. Despite this, the molecular mechanisms of disease remain unknown. METHODS: RNA sequencing (RNAseq) w...

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Detalles Bibliográficos
Autores principales: Levin, Anna, Reznichenko, Anna, Witasp, Anna, Liu, Peidi, Greasley, Peter J, Sorrentino, Antonio, Blondal, Thorarinn, Zambrano, Sonia, Nordström, Johan, Bruchfeld, Annette, Barany, Peter, Ebefors, Kerstin, Erlandsson, Fredrik, Patrakka, Jaakko, Stenvinkel, Peter, Nyström, Jenny, Wernerson, Annika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716805/
https://www.ncbi.nlm.nih.gov/pubmed/32853351
http://dx.doi.org/10.1093/ndt/gfaa121