BRD4 modulates vulnerability of triple-negative breast cancer to targeting of integrin-dependent signaling pathways

PURPOSE: Stemming from a myriad of genetic and epigenetic alterations, triple-negative breast cancer (TNBC) is tied to poor clinical outcomes and aspires for individualized therapies. Here we investigated the therapeutic potential of co-inhibiting integrin-dependent signaling pathway and BRD4, a tra...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Xu, Bingwei, Shi, Junfeng, Li, Jieming, Lu, Xinlan, Xu, Li, Yang, Helen, Hamad, Nevean, Wang, Chi, Napier, Dana, He, Shuixiang, Liu, Chunming, Liu, Zeyi, Qian, Hai, Chen, Li, Wei, Xiaowei, Zheng, Xucai, Huang, Jian-An, Thibault, Olivier, Craven, Rolf, Wei, Dongping, Pan, Yueyin, Zhou, Binhua P., Wu, Yadi, Yang, Xiuwei H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716866/
https://www.ncbi.nlm.nih.gov/pubmed/33006750
http://dx.doi.org/10.1007/s13402-020-00537-1

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