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Time-dependent solution of the NIMFA equations around the epidemic threshold
The majority of epidemic models are described by non-linear differential equations which do not have a closed-form solution. Due to the absence of a closed-form solution, the understanding of the precise dynamics of a virus is rather limited. We solve the differential equations of the N-intertwined...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716943/ https://www.ncbi.nlm.nih.gov/pubmed/32959068 http://dx.doi.org/10.1007/s00285-020-01542-6 |
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author | Prasse, Bastian Van Mieghem, Piet |
author_facet | Prasse, Bastian Van Mieghem, Piet |
author_sort | Prasse, Bastian |
collection | PubMed |
description | The majority of epidemic models are described by non-linear differential equations which do not have a closed-form solution. Due to the absence of a closed-form solution, the understanding of the precise dynamics of a virus is rather limited. We solve the differential equations of the N-intertwined mean-field approximation of the susceptible-infected-susceptible epidemic process with heterogeneous spreading parameters around the epidemic threshold for an arbitrary contact network, provided that the initial viral state vector is small or parallel to the steady-state vector. Numerical simulations demonstrate that the solution around the epidemic threshold is accurate, also above the epidemic threshold and for general initial viral states that are below the steady-state. |
format | Online Article Text |
id | pubmed-7716943 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-77169432020-12-04 Time-dependent solution of the NIMFA equations around the epidemic threshold Prasse, Bastian Van Mieghem, Piet J Math Biol Article The majority of epidemic models are described by non-linear differential equations which do not have a closed-form solution. Due to the absence of a closed-form solution, the understanding of the precise dynamics of a virus is rather limited. We solve the differential equations of the N-intertwined mean-field approximation of the susceptible-infected-susceptible epidemic process with heterogeneous spreading parameters around the epidemic threshold for an arbitrary contact network, provided that the initial viral state vector is small or parallel to the steady-state vector. Numerical simulations demonstrate that the solution around the epidemic threshold is accurate, also above the epidemic threshold and for general initial viral states that are below the steady-state. Springer Berlin Heidelberg 2020-09-22 2020 /pmc/articles/PMC7716943/ /pubmed/32959068 http://dx.doi.org/10.1007/s00285-020-01542-6 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Prasse, Bastian Van Mieghem, Piet Time-dependent solution of the NIMFA equations around the epidemic threshold |
title | Time-dependent solution of the NIMFA equations around the epidemic threshold |
title_full | Time-dependent solution of the NIMFA equations around the epidemic threshold |
title_fullStr | Time-dependent solution of the NIMFA equations around the epidemic threshold |
title_full_unstemmed | Time-dependent solution of the NIMFA equations around the epidemic threshold |
title_short | Time-dependent solution of the NIMFA equations around the epidemic threshold |
title_sort | time-dependent solution of the nimfa equations around the epidemic threshold |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716943/ https://www.ncbi.nlm.nih.gov/pubmed/32959068 http://dx.doi.org/10.1007/s00285-020-01542-6 |
work_keys_str_mv | AT prassebastian timedependentsolutionofthenimfaequationsaroundtheepidemicthreshold AT vanmieghempiet timedependentsolutionofthenimfaequationsaroundtheepidemicthreshold |