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Hashimoto encephalopathy: a case report and a short revision of current literature

Hashimoto encephalopathy (HE) is a rare but controversial entity encompassing a variety of neuropsychological presentations in the setting of autoimmune thyroid disease. HE, mostly described in adults, with a female-to-male ratio of 4:1, is a relatively rare entity in the pediatric population and pr...

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Autores principales: Chiarello, Paola, Talarico, Valentina, Nicoletti, Angela, Rodio, Benedetta, Arcuri, Pier Paolo, Bosco, Domenico, Gigliotti, Francesco, Galati, Maria Concetta, Raiola, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717026/
https://www.ncbi.nlm.nih.gov/pubmed/32921783
http://dx.doi.org/10.23750/abm.v91i3.10157
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author Chiarello, Paola
Talarico, Valentina
Nicoletti, Angela
Rodio, Benedetta
Arcuri, Pier Paolo
Bosco, Domenico
Gigliotti, Francesco
Galati, Maria Concetta
Raiola, Giuseppe
author_facet Chiarello, Paola
Talarico, Valentina
Nicoletti, Angela
Rodio, Benedetta
Arcuri, Pier Paolo
Bosco, Domenico
Gigliotti, Francesco
Galati, Maria Concetta
Raiola, Giuseppe
author_sort Chiarello, Paola
collection PubMed
description Hashimoto encephalopathy (HE) is a rare but controversial entity encompassing a variety of neuropsychological presentations in the setting of autoimmune thyroid disease. HE, mostly described in adults, with a female-to-male ratio of 4:1, is a relatively rare entity in the pediatric population and probably under recognized as a cause of acute encephalopathy in children and adolescents. A number of pathogenetic mechanisms have been suggested. Female prevalence, presence of autoantibodies, fluctuating course, and response to immunomodulatory therapy suggest the autoimmune nature of the disease. Existing diagnostic criteria for adults require modification to be applied to children and adolescents, who differ from adults in their clinical presentations, clinical findings, autoantibody profiles, treatment response, and long-term outcomes. A combination of neurological findings, positive antithyroid autoantibodies, and responsiveness to steroids is diagnostic of HE. We add a new case of HE in an adolescent girl and review the current HE literature. (www.actabiomedica.it)
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spelling pubmed-77170262020-12-07 Hashimoto encephalopathy: a case report and a short revision of current literature Chiarello, Paola Talarico, Valentina Nicoletti, Angela Rodio, Benedetta Arcuri, Pier Paolo Bosco, Domenico Gigliotti, Francesco Galati, Maria Concetta Raiola, Giuseppe Acta Biomed Case Report Hashimoto encephalopathy (HE) is a rare but controversial entity encompassing a variety of neuropsychological presentations in the setting of autoimmune thyroid disease. HE, mostly described in adults, with a female-to-male ratio of 4:1, is a relatively rare entity in the pediatric population and probably under recognized as a cause of acute encephalopathy in children and adolescents. A number of pathogenetic mechanisms have been suggested. Female prevalence, presence of autoantibodies, fluctuating course, and response to immunomodulatory therapy suggest the autoimmune nature of the disease. Existing diagnostic criteria for adults require modification to be applied to children and adolescents, who differ from adults in their clinical presentations, clinical findings, autoantibody profiles, treatment response, and long-term outcomes. A combination of neurological findings, positive antithyroid autoantibodies, and responsiveness to steroids is diagnostic of HE. We add a new case of HE in an adolescent girl and review the current HE literature. (www.actabiomedica.it) Mattioli 1885 2020 2020-09-07 /pmc/articles/PMC7717026/ /pubmed/32921783 http://dx.doi.org/10.23750/abm.v91i3.10157 Text en Copyright: © 2020 ACTA BIO MEDICA SOCIETY OF MEDICINE AND NATURAL SCIENCES OF PARMA http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License
spellingShingle Case Report
Chiarello, Paola
Talarico, Valentina
Nicoletti, Angela
Rodio, Benedetta
Arcuri, Pier Paolo
Bosco, Domenico
Gigliotti, Francesco
Galati, Maria Concetta
Raiola, Giuseppe
Hashimoto encephalopathy: a case report and a short revision of current literature
title Hashimoto encephalopathy: a case report and a short revision of current literature
title_full Hashimoto encephalopathy: a case report and a short revision of current literature
title_fullStr Hashimoto encephalopathy: a case report and a short revision of current literature
title_full_unstemmed Hashimoto encephalopathy: a case report and a short revision of current literature
title_short Hashimoto encephalopathy: a case report and a short revision of current literature
title_sort hashimoto encephalopathy: a case report and a short revision of current literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717026/
https://www.ncbi.nlm.nih.gov/pubmed/32921783
http://dx.doi.org/10.23750/abm.v91i3.10157
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