Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle

The opportunistic pathogen Streptococcus pneumoniae has dual lifestyles: one of an asymptomatic colonizer in the human nasopharynx and the other of a deadly pathogen invading sterile host compartments. The latter triggers an overwhelming inflammatory response, partly driven via pore forming activity...

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Detalles Bibliográficos
Autores principales: Badgujar, Dilip C., Anil, Anjali, Green, Angharad E., Surve, Manalee Vishnu, Madhavan, Shilpa, Beckett, Alison, Prior, Ian A., Godsora, Barsa K., Patil, Sanket B., More, Prachi Kadam, Sarkar, Shruti Guha, Mitchell, Andrea, Banerjee, Rinti, Phale, Prashant S., Mitchell, Timothy J., Neill, Daniel R., Bhaumik, Prasenjit, Banerjee, Anirban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717573/
https://www.ncbi.nlm.nih.gov/pubmed/33216805
http://dx.doi.org/10.1371/journal.ppat.1009016

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