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Cinnamic acid derivatives: inhibitory activity against Escherichia coli β-glucuronidase and structure–activity relationships

Gut microbial β-glucuronidase (GUS) is a potential therapeutic target to reduce gastrointestinal toxicity caused by irinotecan. In this study, the inhibitory effects of 17 natural cinnamic acid derivatives on Escherichia coli GUS (EcGUS) were characterised. Seven compounds, including caffeic acid et...

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Detalles Bibliográficos
Autores principales:	Li, Xing-Nuo, Hua, Lu-Xia, Zhou, Tao-Shun, Wang, Ke-Bo, Wu, Yuan-Yuan, Emam, Mahmoud, Bao, Xiao-Ze, Chen, Jun, Wei, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717682/ https://www.ncbi.nlm.nih.gov/pubmed/32571102 http://dx.doi.org/10.1080/14756366.2020.1780225

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