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The actin-modulating protein synaptopodin mediates long-term survival of dendritic spines

Large spines are stable and important for memory trace formation. The majority of large spines also contains synaptopodin (SP), an actin-modulating and plasticity-related protein. Since SP stabilizes F-actin, we speculated that the presence of SP within large spines could explain their long lifetime...

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Detalles Bibliográficos
Autores principales: Yap, Kenrick, Drakew, Alexander, Smilovic, Dinko, Rietsche, Michael, Paul, Mandy H, Vuksic, Mario, Del Turco, Domenico, Deller, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717903/
https://www.ncbi.nlm.nih.gov/pubmed/33275099
http://dx.doi.org/10.7554/eLife.62944

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