Increased processing of SINE B2 ncRNAs unveils a novel type of transcriptome deregulation in amyloid beta neuropathology

The functional importance of many non-coding RNAs (ncRNAs) generated by repetitive elements and their connection with pathologic processes remains elusive. B2 RNAs, a class of ncRNAs of the B2 family of SINE repeats, mediate through their processing the transcriptional activation of various genes in...

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Detalles Bibliográficos
Autores principales: Cheng, Yubo, Saville, Luke, Gollen, Babita, Isaac, Christopher, Belay, Abel, Mehla, Jogender, Patel, Kush, Thakor, Nehal, Mohajerani, Majid H, Zovoilis, Athanasios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717908/
https://www.ncbi.nlm.nih.gov/pubmed/33191914
http://dx.doi.org/10.7554/eLife.61265

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