The Rare YAP1 Subtype of SCLC Revisited in a Biobank of 39 Circulating Tumor Cell Patient Derived Explant Models: A Brief Report

INTRODUCTION: Recent consensus defines four SCLC subtypes on the basis of transcription factor expression: ASCL1, NEUROD1, POU2F3, and YAP1. The rare YAP1 subtype is associated with “neuroendocrine (NE)-low” cells among SCLC cell lines and patient samples. We evaluated YAP1 in 39 patients with pheno...

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Detalles Bibliográficos
Autores principales: Pearsall, Sarah M., Humphrey, Sam, Revill, Mitchell, Morgan, Derrick, Frese, Kristopher K., Galvin, Melanie, Kerr, Alastair, Carter, Mathew, Priest, Lynsey, Blackhall, Fiona, Simpson, Kathryn L., Dive, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Small Cell Lung Cancer Subtypes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718082/
https://www.ncbi.nlm.nih.gov/pubmed/32721553
http://dx.doi.org/10.1016/j.jtho.2020.07.008

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