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Risk prediction model of gestational diabetes mellitus based on nomogram in a Chinese population cohort study

To build a risk prediction model of gestational diabetes mellitus using nomogram to provide a simple-to-use clinical basis for the early prediction of gestational diabetes mellitus (GDM). This study is a prospective cohort study including 1385 pregnant women. (1) It is showed that the risk of GDM in...

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Autores principales: Zhang, Xiaomei, Zhao, Xin, Huo, Lili, Yuan, Ning, Sun, Jianbin, Du, Jing, Nan, Min, Ji, Linong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718223/
https://www.ncbi.nlm.nih.gov/pubmed/33277541
http://dx.doi.org/10.1038/s41598-020-78164-x
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author Zhang, Xiaomei
Zhao, Xin
Huo, Lili
Yuan, Ning
Sun, Jianbin
Du, Jing
Nan, Min
Ji, Linong
author_facet Zhang, Xiaomei
Zhao, Xin
Huo, Lili
Yuan, Ning
Sun, Jianbin
Du, Jing
Nan, Min
Ji, Linong
author_sort Zhang, Xiaomei
collection PubMed
description To build a risk prediction model of gestational diabetes mellitus using nomogram to provide a simple-to-use clinical basis for the early prediction of gestational diabetes mellitus (GDM). This study is a prospective cohort study including 1385 pregnant women. (1) It is showed that the risk of GDM in women aged ≥ 35 years was 5.5 times higher than that in women aged < 25 years (95% CI: 1.27–23.73, p < 0.05). In the first trimester, the risk of GDM in women with abnormal triglyceride who were in their first trimester was 2.1 times higher than that of lipid normal women (95% CI: 1.12–3.91, p < 0.05). The area under the ROC curve of the nomogram of was 0.728 (95% CI: 0.683–0.772), the sensitivity and specificity of the model were 0.716 and 0.652, respectively. This study provides a simple and economic nomogram for the early prediction of GDM risk in the first trimester, and it has certain accuracy.
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spelling pubmed-77182232020-12-08 Risk prediction model of gestational diabetes mellitus based on nomogram in a Chinese population cohort study Zhang, Xiaomei Zhao, Xin Huo, Lili Yuan, Ning Sun, Jianbin Du, Jing Nan, Min Ji, Linong Sci Rep Article To build a risk prediction model of gestational diabetes mellitus using nomogram to provide a simple-to-use clinical basis for the early prediction of gestational diabetes mellitus (GDM). This study is a prospective cohort study including 1385 pregnant women. (1) It is showed that the risk of GDM in women aged ≥ 35 years was 5.5 times higher than that in women aged < 25 years (95% CI: 1.27–23.73, p < 0.05). In the first trimester, the risk of GDM in women with abnormal triglyceride who were in their first trimester was 2.1 times higher than that of lipid normal women (95% CI: 1.12–3.91, p < 0.05). The area under the ROC curve of the nomogram of was 0.728 (95% CI: 0.683–0.772), the sensitivity and specificity of the model were 0.716 and 0.652, respectively. This study provides a simple and economic nomogram for the early prediction of GDM risk in the first trimester, and it has certain accuracy. Nature Publishing Group UK 2020-12-04 /pmc/articles/PMC7718223/ /pubmed/33277541 http://dx.doi.org/10.1038/s41598-020-78164-x Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Zhang, Xiaomei
Zhao, Xin
Huo, Lili
Yuan, Ning
Sun, Jianbin
Du, Jing
Nan, Min
Ji, Linong
Risk prediction model of gestational diabetes mellitus based on nomogram in a Chinese population cohort study
title Risk prediction model of gestational diabetes mellitus based on nomogram in a Chinese population cohort study
title_full Risk prediction model of gestational diabetes mellitus based on nomogram in a Chinese population cohort study
title_fullStr Risk prediction model of gestational diabetes mellitus based on nomogram in a Chinese population cohort study
title_full_unstemmed Risk prediction model of gestational diabetes mellitus based on nomogram in a Chinese population cohort study
title_short Risk prediction model of gestational diabetes mellitus based on nomogram in a Chinese population cohort study
title_sort risk prediction model of gestational diabetes mellitus based on nomogram in a chinese population cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718223/
https://www.ncbi.nlm.nih.gov/pubmed/33277541
http://dx.doi.org/10.1038/s41598-020-78164-x
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