Cargando…

Degradation of connexin 50 protein causes waterclefts in human lens

Cataracts are mainly classified into three types: cortical cataracts, nuclear cataracts, and posterior subcapsular cataracts. In addition, retrodots and waterclefts are cataract subtypes that cause decreased visual function. To maintain an orderly and tightly packed arrangement to minimize light sca...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nakazawa, Yosuke, Shibata, Teppei, Nagai, Noriaki, Kubo, Eri, Tamura, Hiroomi, Sasaki, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	De Gruyter 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718650/ https://www.ncbi.nlm.nih.gov/pubmed/33336073 http://dx.doi.org/10.1515/med-2020-0249

Ejemplares similares

Analyzing Effect of Waterclefts on Visual Functions Via Optical Simulations
por: Seki, Yusuke, et al.
Publicado: (2022)

Enhancement of Amyloid β(1–43) Production in the Lens Epithelium of Japanese Type 2 Diabetic Patients
por: Mano, Yu, et al.
Publicado: (2020)

Oral consumption of α-glucosyl-hesperidin could prevent lens hardening, which causes presbyopia
por: Nakazawa, Yosuke, et al.
Publicado: (2020)

Role of Decorin in the Lens and Ocular Diseases
por: Kubo, Eri, et al.
Publicado: (2022)

Hesperetin treatment attenuates glycation of lens proteins and advanced‑glycation end products generation
por: Doki, Yuri, et al.
Publicado: (2023)

Regulation of the Membrane Trafficking of the Mechanosensitive Ion Channels TRPV1 and TRPV4 by Zonular Tension, Osmotic Stress and Activators in the Mouse Lens
por: Nakazawa, Yosuke, et al.
Publicado: (2021)

Effect of a Lens Protein in Low-Temperature Culture of Novel Immortalized Human Lens Epithelial Cells (iHLEC-NY2)
por: Yamamoto, Naoki, et al.
Publicado: (2020)

Roles of TGF β and FGF Signals in the Lens: Tropomyosin Regulation for Posterior Capsule Opacity
por: Kubo, Eri, et al.
Publicado: (2018)

Effect of Alpha-Glucosyl-Hesperidin Consumption on Lens Sclerosis and Presbyopia
por: Nakazawa, Yosuke, et al.
Publicado: (2021)

Lutein plus Water Chestnut (Trapa bispinosa Roxb.) Extract Inhibits the Development of Cataracts and Induces Antioxidant Gene Expression in Lens Epithelial Cells
por: Ishida, Hidetoshi, et al.
Publicado: (2020)

Quantitative assessment of photic phenomena in the presbyopia-correcting intraocular lens
por: Ukai, Yuki, et al.
Publicado: (2021)

Identification of Differential Gene Expression Pattern in Lens Epithelial Cells Derived from Cataractous and Noncataractous Lenses of Shumiya Cataract Rat
por: Ishida, Hidetoshi, et al.
Publicado: (2020)

Connexin 50 Functions as an Adhesive Molecule and Promotes Lens Cell Differentiation
por: Hu, Zhengping, et al.
Publicado: (2017)

Function of mitochondrial cytochrome c oxidase is enhanced in human lens epithelial cells at high temperatures
por: Takeda, Shun, et al.
Publicado: (2022)

Instillation of Ophthalmic Formulation Containing Nilvadipine Nanocrystals Attenuates Lens Opacification in Shumiya Cataract Rats
por: Goto, Ryoka, et al.
Publicado: (2021)

Combination of Lanosterol and Nilvadipine Nanosuspensions Rescues Lens Opacification in Selenite-Induced Cataractic Rats
por: Deguchi, Saori, et al.
Publicado: (2022)

Structure of native lens connexin-46/50 intercellular channels by CryoEM
por: Myers, Janette B., et al.
Publicado: (2018)

Connexin 50 and AQP0 are Essential in Maintaining Organization and Integrity of Lens Fibers
por: Gu, Sumin, et al.
Publicado: (2019)

CHOP is dispensable for lens transparency in wild-type and connexin50 mutant mice
por: Minogue, Peter J., et al.
Publicado: (2019)

Beyond the Channels: Adhesion Functions of Aquaporin 0 and Connexin 50 in Lens Development
por: Li, Zhen, et al.
Publicado: (2022)

Connexin hemichannels in the lens
por: Beyer, Eric C., et al.
Publicado: (2014)

Focus on lens connexins
por: Berthoud, Viviana M., et al.
Publicado: (2017)

Role of Decorin in Posterior Capsule Opacification and Eye Lens Development
por: Shibata, Shinsuke, et al.
Publicado: (2021)

Acute cataract by a high-intensity focused ultrasound procedure: a case report
por: Ikoma, Toru, et al.
Publicado: (2022)

Connexin 50-R205G Mutation Perturbs Lens Epithelial Cell Proliferation and Differentiation
por: Tjahjono, Nikki, et al.
Publicado: (2020)

FGF2 antagonizes aberrant TGFβ regulation of tropomyosin: role for posterior capsule opacity
por: Kubo, Eri, et al.
Publicado: (2016)

Oral intake of α-glucosyl-hesperidin ameliorates selenite-induced cataract formation
por: Nakazawa, Yosuke, et al.
Publicado: (2020)

The second extracellular domain of connexin 50 is important for in cell adhesion, lens differentiation, and adhesion molecule expression
por: Li, Zhen, et al.
Publicado: (2023)

Connexin Mutants Compromise the Lens Circulation and Cause Cataracts through Biomineralization
por: Berthoud, Viviana M., et al.
Publicado: (2020)

Propolis, a Constituent of Honey, Inhibits the Development of Sugar Cataracts and High-Glucose-Induced Reactive Oxygen Species in Rat Lenses
por: Shibata, Teppei, et al.
Publicado: (2016)

Distinctive actions of connexin 46 and connexin 50 in anterior pituitary folliculostellate cells
por: Vitale, María Leiza, et al.
Publicado: (2017)

Dynamic and differential regulation in the microRNA expression in the developing and mature cataractous rat lens
por: Kubo, Eri, et al.
Publicado: (2013)

The Connexin50D47A Mutant Causes Cataracts by Calcium Precipitation
por: Berthoud, Viviana M., et al.
Publicado: (2019)

Effect of hesperetin on chaperone activity in selenite-induced cataract
por: Nakazawa, Yosuke, et al.
Publicado: (2016)

Connections Between Connexins, Calcium, and Cataracts in the Lens
por: Gao, Junyuan, et al.
Publicado: (2004)

Levels and Modifications of Both Lens Fiber Cell Connexins Are Affected in Connexin Mutant Mice
por: Jara, Oscar, et al.
Publicado: (2022)

Elevated tropomyosin expression is associated with epithelial–mesenchymal transition of lens epithelial cells
por: Kubo, Eri, et al.
Publicado: (2013)

Do Connexin Mutants Cause Cataracts by Perturbing Glutathione Levels and Redox Metabolism in the Lens?
por: Jara, Oscar, et al.
Publicado: (2020)

Connexin43 and connexin50 channels exhibit different permeability to the second messenger inositol triphosphate
por: Valiunas, Virginijus, et al.
Publicado: (2020)

Connexins, Cell Proliferation and Second Messengers in the Crystalline Lens
por: White, Thomas W
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_r8c76bttevu4vfuvc3muemijjd