Maintenance of Cell Fate by the Polycomb Group Gene Sex Combs Extra Enables a Partial Epithelial Mesenchymal Transition in Drosophila

Epigenetic silencing by Polycomb group (PcG) complexes can promote epithelial-mesenchymal transition (EMT) and stemness and is associated with malignancy of solid cancers. Here we report a role for Drosophila PcG repression in a partial EMT event that occurs during wing disc eversion, an early event...

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Detalles Bibliográficos
Autores principales: Jefferies, Grace, Somers, Jason, Lohrey, Isabelle, Chaturvedi, Vishal, Calabria, Jacob, Marshall, Owen J., Southall, Tony D., Saint, Robert, Murray, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718746/
https://www.ncbi.nlm.nih.gov/pubmed/33051260
http://dx.doi.org/10.1534/g3.120.401785

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