Slow Growth and Increased Spontaneous Mutation Frequency in Respiratory Deficient afo1(-) Yeast Suppressed by a Dominant Mutation in ATP3

A yeast deletion mutation in the nuclear-encoded gene, AFO1, which codes for a mitochondrial ribosomal protein, led to slow growth on glucose, the inability to grow on glycerol or ethanol, and loss of mitochondrial DNA and respiration. We noticed that afo1(-) yeast readily obtains secondary mutation...

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Detalles Bibliográficos
Autores principales: Li, Jing, Rinnerthaler, Mark, Hartl, Johannes, Weber, Manuela, Karl, Thomas, Breitenbach-Koller, Hannelore, Mülleder, Michael, Vowinckel, Jakob, Marx, Hans, Sauer, Michael, Mattanovich, Diethard, Ata, Özge, De, Sonakshi, Greslehner, Gregor P., Geltinger, Florian, Burhans, Bill, Grant, Chris, Doronina, Victoria, Ralser, Meryem, Streubel, Maria Karolin, Grabner, Christian, Jarolim, Stefanie, Moßhammer, Claudia, Gourlay, Campbell W., Hasek, Jiri, Cullen, Paul J., Liti, Gianni, Ralser, Markus, Breitenbach, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718765/
https://www.ncbi.nlm.nih.gov/pubmed/33093184
http://dx.doi.org/10.1534/g3.120.401537

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