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Changes in Class I and IIb HDACs by δ-Opioid in Chronic Rat Glaucoma Model

PURPOSE: This study determines if δ-opioid receptor agonist (i.e. SNC-121)-induced epigenetic changes via regulation of histone deacetylases (HDACs) for retinal ganglion cell (RGC) neuroprotection in glaucoma model. METHODS: Intraocular pressure was raised in rat eyes by injecting 2M hypertonic sali...

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Detalles Bibliográficos
Autores principales:	Zaidi, Syed A. H., Guzman, Wendy, Singh, Sudha, Mehrotra, Shikhar, Husain, Shahid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2020
Materias:	Physiology and Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718808/ https://www.ncbi.nlm.nih.gov/pubmed/33263714 http://dx.doi.org/10.1167/iovs.61.14.4

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