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Stress Signal Regulation by Na/K-ATPase As a New Approach to Promote Physiological Revascularization in a Mouse Model of Ischemic Retinopathy

PURPOSE: The identification of target pathways to block excessive angiogenesis while simultaneously restoring physiological vasculature is an unmet goal in the therapeutic management of ischemic retinopathies. pNaKtide, a cell-permeable peptide that we have designed by mapping the site of α1 Na/K-AT...

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Detalles Bibliográficos
Autores principales: Wang, Jiayan, Wang, Xiaoliang, Gao, Yingnyu, Lin, Zhucheng, Chen, Jing, Gigantelli, James, Shapiro, Joseph I., Xie, Zijian, Pierre, Sandrine V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718810/
https://www.ncbi.nlm.nih.gov/pubmed/33275652
http://dx.doi.org/10.1167/iovs.61.14.9