Cargando…

Mechanism of Action of Bu-Fei-Yi-Shen Formula in Treating Chronic Obstructive Pulmonary Disease Based on Network Pharmacology Analysis and Molecular Docking Validation

OBJECTIVE: To explore the mechanism of action of Bu-Fei-Yi-Shen formula (BFYSF) in treating chronic obstructive pulmonary disease (COPD) based on network pharmacology analysis and molecular docking validation. METHODS: First of all, the pharmacologically active ingredients and corresponding targets...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Longchuan, Chen, Yu, Yi, Jiao, Zhuang, Yi, Cui, Lei, Ye, Chunhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718855/ https://www.ncbi.nlm.nih.gov/pubmed/33313323 http://dx.doi.org/10.1155/2020/9105972

Ejemplares similares

Bu-Fei Yi-Shen Granules Reduce Acute Exacerbations in Patients with GOLD 3–4 COPD: A Randomized Controlled Trial
por: Yu, Xue-Qing, et al.
Publicado: (2023)

Study on the Anti-demyelination Mechanism of Bu-Shen-Yi-Sui Capsule in the Central Nervous System Based on Network Pharmacology and Experimental Verification
por: Zha, Zheng, et al.
Publicado: (2022)

RNA-Seq Expression Analysis of Chronic Asthmatic Mice with Bu-Shen-Yi-Qi Formula Treatment and Prediction of Regulated Gene Targets of Anti-Airway Remodeling
por: Cui, Jie, et al.
Publicado: (2021)

Tiao-Bu-Fei-Shen Formula Improves Glucocorticoid Resistance of Chronic Obstructive Pulmonary Disease via Downregulating the PI3K-Akt Signaling Pathway and Promoting GRα Expression
por: Zhou, Pengcheng, et al.
Publicado: (2023)

Exploring the Mechanisms of Modified Bu-Shen-Yi-Qi Decoction for COPD-Related Osteoporosis Therapy via Transcriptomics and Network Pharmacology Approach
por: Zhong, Yuanyuan, et al.
Publicado: (2023)

Exploring the comorbidity mechanisms between asthma and idiopathic pulmonary fibrosis and the pharmacological mechanisms of Bu-Shen-Yi-Qi decoction therapy via network pharmacology
por: Zhong, Yuanyuan, et al.
Publicado: (2022)

Bu-Shen-Yi-Sui Capsule, an Herbal Medicine Formula, Promotes Remyelination by Modulating the Molecular Signals via Exosomes in Mice with Experimental Autoimmune Encephalomyelitis
por: Zhao, Pei-Yuan, et al.
Publicado: (2020)

Mechanisms and Molecular Targets of BuShenHuoXue Formula for Osteoarthritis
por: Xiong, Wen, et al.
Publicado: (2022)

Bu-Fei decoction and modified Bu-Fei decoction inhibit the growth of non-small cell lung cancer, possibly via inhibition of apurinic/apyrimidinic endonuclease 1
por: Jiang, Shan-Tong, et al.
Publicado: (2018)

Reveal the Mechanisms of Yi-Fei-Jian-Pi-Tang on Covid-19 through Network Pharmacology Approach
por: Lang, Wanying, et al.
Publicado: (2022)

Mechanism of Fei-Xian Formula in the Treatment of Pulmonary Fibrosis on the Basis of Network Pharmacology Analysis Combined with Molecular Docking Validation
por: Chen, Xiao-Li, et al.
Publicado: (2021)

Long-term effects of three Tiao-Bu Fei-Shen therapies on NF-κB/TGF-β1/smad2 signaling in rats with chronic obstructive pulmonary disease
por: Li, Ya, et al.
Publicado: (2014)

Bu Shen Yi Sui Capsule Promotes Myelin Repair by Modulating the Transformation of A1/A2 Reactive Astrocytes In Vivo and In Vitro
por: Zha, Zheng, et al.
Publicado: (2022)

The Bu Shen Yi Sui Formula Promotes Axonal Regeneration via Regulating the Neurotrophic Factor BDNF/TrkB and the Downstream PI3K/Akt Signaling Pathway
por: Zheng, Qi, et al.
Publicado: (2019)

Network Pharmacology and Experimental Verification Strategies to Illustrate the Mechanism of Jian-Pi-Yi-Shen Formula in Suppressing Epithelial–Mesenchymal Transition
por: Zhao, Yuan, et al.
Publicado: (2022)

Identifying roles of “Jun-Chen-Zuo-Shi” component herbs of QiShenYiQi formula in treating acute myocardial ischemia by network pharmacology
por: Wu, Leihong, et al.
Publicado: (2014)

Jian-Pi-Yi-Shen Formula ameliorates chronic kidney disease: involvement of mitochondrial quality control network
por: Liu, Xinhui, et al.
Publicado: (2018)

BuShenYiQi Granule Inhibits Atopic Dermatitis via Improving Central and Skin Hypothalamic -Pituitary -Adrenal Axis Function
por: Kong, Lingwen, et al.
Publicado: (2015)

Correction: BuShenYiQi Granule Inhibits Atopic Dermatitis via Improving Central and Skin Hypothalamic -Pituitary -Adrenal Axis Function
por: Kong, Lingwen, et al.
Publicado: (2015)

Effects of Bu Shen Yi Sui Capsule on Th17/Treg cytokines in C57BL/6 mice with experimental autoimmune encephalomyelitis
por: Zheng, Qi, et al.
Publicado: (2015)

A Mechanism Exploration for the Yi-Fei-San-Jie Formula against Non-Small-Cell Lung Cancer Based on UPLC-MS/MS, Network Pharmacology, and In Silico Verification
por: Hu, Leihao, et al.
Publicado: (2023)

Pharmaceutical and pharmacological studies of Shen Ma Yi Zhi granule for prevention of vascular dementia: A review
por: Chang, Su-rui, et al.
Publicado: (2022)

Effects of Bu Shen Yi sui capsule on NogoA/NgR and its signaling pathways RhoA/ROCK in mice with experimental autoimmune encephalomyelitis
por: Fang, Ling, et al.
Publicado: (2017)

Bu Shen Yi Sui Capsules Promote Remyelination by Regulating MicroRNA-219 and MicroRNA-338 in Exosomes to Promote Oligodendrocyte Precursor Cell Differentiation
por: Ji, Jing, et al.
Publicado: (2022)

Jian-Pi-Yi-Fei granule suppresses airway inflammation in mice induced by cigarette smoke condensate and lipopolysaccharide
por: Tang, Cui-Ying, et al.
Publicado: (2019)

Shi's Yi-Qi Bu-Shen Tong-Luo decoction combined with manipulation in the management of wrist stiffness after distal radius fracture: Study protocol clinical trial (SPIRIT Compliant)
por: Wu, Hai-Yang, et al.
Publicado: (2020)

The mechanism of TiaoGanYiPi formula for treating chronic hepatitis B by network pharmacology and molecular docking verification
por: Cao, Xu, et al.
Publicado: (2021)

Investigating the active compounds and mechanism of HuaShi XuanFei formula for prevention and treatment of COVID-19 based on network pharmacology and molecular docking analysis
por: Wang, Juan, et al.
Publicado: (2021)

A Network Pharmacology Approach to Explore the Mechanism of HuangZhi YiShen Capsule for Treatment of Diabetic Kidney Disease
por: Zhou, Xue-Feng, et al.
Publicado: (2021)

Modified BuShenYiQi formula alleviates experimental allergic asthma in mice by negative regulation of type 2 innate lymphoid cells and CD4(+) type 9 helper T cells and the VIP–VPAC2 signalling pathway
por: Huang, Muhua, et al.
Publicado: (2021)

Protective Effects of Bu-Shen-Huo-Xue Formula against 5/6 Nephrectomy-Induced Chronic Renal Failure in Rats
por: Lu, Jian-Rao, et al.
Publicado: (2014)

Bu-Fei-Huo-Xue capsule alleviates bleomycin-induced pulmonary fibrosis in mice through modulating gut microbiota
por: Hu, Haibo, et al.
Publicado: (2023)

Involvement of Circulating Exosomal MicroRNAs in Jian-Pi-Yi-Shen Formula Protection Against Adenine-Induced Chronic Kidney Disease
por: Liu, Xinhui, et al.
Publicado: (2021)

Protective effects and regulatory mechanisms of Shen-shuai-yi recipe on renal fibrosis in unilateral ureteral obstruction-induced mice
por: Lin, Ping-lan, et al.
Publicado: (2023)

Study on the Mechanism of Qing-Fei-Shen-Shi Decoction on Asthma Based on Integrated 16S rRNA Sequencing and Untargeted Metabolomics
por: Hu, Haibo, et al.
Publicado: (2023)

Identification of the Active Constituents and Significant Pathways of Shen-qi-Yi-zhu Decoction on Antigastric Cancer: A Network Pharmacology Research and Experimental Validation
por: Zeng, Shuhong, et al.
Publicado: (2021)

Chinese herbal medicine (Bu-Shen-Tian-Jing Formula) for outcomes of IVF in Chinese patients with polycystic ovary syndrome: a retrospective cohort study
por: Pan, Xiaoming, et al.
Publicado: (2022)

Herbal Formula Modified Bu-Shen-Huo-Xue Decoction Attenuates Intervertebral Disc Degeneration via Regulating Inflammation and Oxidative Stress
por: Lin, Jialiang, et al.
Publicado: (2022)

A Network Pharmacology Study of Chinese Medicine QiShenYiQi to Reveal Its Underlying Multi-Compound, Multi-Target, Multi-Pathway Mode of Action
por: Li, Xiang, et al.
Publicado: (2014)

Jian-Pi-Yi-Shen Formula Ameliorates Oxidative Stress, Inflammation, and Apoptosis by Activating the Nrf2 Signaling in 5/6 Nephrectomized Rats
por: Zhou, Fanyuan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6tg7dcei67ccv1trgh1p04hr15