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Identification and characterization of antigen-specific CD4(+) T cells targeting renally expressed antigens in human lupus nephritis with two independent methods
In the search for anti-renal autoreactivity in human lupus nephritis, we stimulated blood-derived CD4(+) T cells from patients with systemic lupus erythematosus with various kidney lysates. Although only minor responses were detectable, these experiments led to the development of a search algorithm...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718878/ https://www.ncbi.nlm.nih.gov/pubmed/33277543 http://dx.doi.org/10.1038/s41598-020-78223-3 |