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Overexpression of wild type or a Q311E mutant MB21D2 promotes a pro‐oncogenic phenotype in HNSCC

Cadherin‐mediated cell–cell contacts regulated by intracellular binders play critical roles in tissue homeostasis and tumorigenesis. Here, we screened mutational profiles of 312 annotated genes involved in cadherin binding in human squamous cell carcinomas and found MB21D2 to carry a unique recurren...

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Detalles Bibliográficos
Autores principales: Gracilla, Daniel E., Korla, Praveen Kumar, Lai, Ming‐Tsung, Chiang, An‐Jen, Liou, Wen‐Shiung, Sheu, Jim Jinn‐Chyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718949/
https://www.ncbi.nlm.nih.gov/pubmed/32979859
http://dx.doi.org/10.1002/1878-0261.12806