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Brain TSPO-PET predicts later disease progression independent of relapses in multiple sclerosis
Overactivation of microglia is associated with most neurodegenerative diseases. In this study we examined whether PET-measurable innate immune cell activation predicts multiple sclerosis disease progression. Activation of microglia/macrophages was measured using the 18-kDa translocator protein (TSPO...
Autores principales: | Sucksdorff, Marcus, Matilainen, Markus, Tuisku, Jouni, Polvinen, Eero, Vuorimaa, Anna, Rokka, Johanna, Nylund, Marjo, Rissanen, Eero, Airas, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719021/ https://www.ncbi.nlm.nih.gov/pubmed/33006604 http://dx.doi.org/10.1093/brain/awaa275 |
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