Cargando…
Good Manufacturing Practice‐Grade of Megakaryocytes Produced by a Novel Ex Vivo Culturing Platform
Ex vivo (EV)‐derived megakaryocytes (MKs) have shown great promise as a substitute for platelets in transfusion medicine to alleviate a severe shortage of donor‐platelets. Challenges remain that include poor efficiency, a limited scale of production, and undefined short‐term storage conditions of EV...
Autores principales: | Guan, Xin, Wang, Lan, Wang, Hanlu, Wang, Huihui, Dai, Wei, Jiang, Yongping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719378/ https://www.ncbi.nlm.nih.gov/pubmed/33030809 http://dx.doi.org/10.1111/cts.12788 |
Ejemplares similares
-
Manipulating megakaryocytes to manufacture platelets ex vivo
por: Karagiannis, P, et al.
Publicado: (2015) -
The heterogeneity of megakaryocytes and platelets and implications for ex vivo platelet generation
por: Liu, Cuicui, et al.
Publicado: (2021) -
Evaluation of ex vivo produced endothelial progenitor cells for autologous transplantation in primates
por: Qin, Meng, et al.
Publicado: (2018) -
An effective ex-vivo approach for inducing endothelial progenitor cells from umbilical cord blood CD34(+) cells
por: Qin, Meng, et al.
Publicado: (2017) -
Safety and Efficacy of Megakaryocytes Induced from Hematopoietic Stem Cells in Murine and Nonhuman Primate Models
por: Guan, Xin, et al.
Publicado: (2016)