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Crystal structures of ORFV125 provide insight into orf virus-mediated inhibition of apoptosis

Premature apoptosis of cells is a strategy utilized by multicellular organisms to counter microbial threats. Orf virus (ORFV) is a large double-stranded DNA virus belonging to the poxviridae. ORFV encodes for an apoptosis inhibitory protein ORFV125 homologous to B-cell lymphoma 2 or Bcl-2 family pro...

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Detalles Bibliográficos
Autores principales:	Suraweera, Chathura D., Hinds, Mark G., Kvansakul, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719400/ https://www.ncbi.nlm.nih.gov/pubmed/33175095 http://dx.doi.org/10.1042/BCJ20200776

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