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The Cleaning Effect of the Photocatalysis of TiO(2)-B@anatase Nanowires on Biological Activity on a Titanium Surface
BACKGROUND: Improvements in the early osseointegration of titanium implants require investigations on the bone-implant interface, which is a critical and complex challenge. The surface cleanliness of titanium implants plays an important role at this interface. However, the implant surface would inev...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719464/ https://www.ncbi.nlm.nih.gov/pubmed/33299309 http://dx.doi.org/10.2147/IJN.S275373 |
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author | Gao, Yan Lin, Xi Zhao, Yadong Xu, Shulan Lai, Chunhua Guo, Zehong Wu, Wangxi Ding, Xianglong Jia, Fang Zhou, Lei Liu, Ying |
author_facet | Gao, Yan Lin, Xi Zhao, Yadong Xu, Shulan Lai, Chunhua Guo, Zehong Wu, Wangxi Ding, Xianglong Jia, Fang Zhou, Lei Liu, Ying |
author_sort | Gao, Yan |
collection | PubMed |
description | BACKGROUND: Improvements in the early osseointegration of titanium implants require investigations on the bone-implant interface, which is a critical and complex challenge. The surface cleanliness of titanium implants plays an important role at this interface. However, the implant surface would inevitably absorb contamination such as organic hydrocarbons, which is not conductive to the establishment of early osseointegration. Herein, an optimized approach for removing contamination from titanium surfaces was studied. METHODS: The TiO(2)-B@anatase NWs (nanowires) were prepared on titanium substrates through a hydrothermal process. A methylene blue degradation experiment was performed to assess the photodegradation activity. The cleaning effect of the photocatalysis of TiO(2)-B@anatase NWs on a titanium surface and the cellular early response was determined by analyzing cell morphology, attachment, proliferation and differentiation. RESULTS: The results indicated that the photocatalysis of TiO(2)-B@anatase NWs could effectively remove hydrocarbons on titanium surfaces without sacrificing the favourable titanium surface morphology. The methylene blue degradation experiment revealed that the photocatalysis of TiO(2)-B@anatase NWs had powerful degradation activity, which is attributed to the presence of strong oxidants such as (·)OH. In addition, compared to the merely ultraviolet-treated titanium surfaces, the titanium surfaces treated after the NWs photocatalytic cleaning process markedly enhanced cellular early response. CONCLUSION: The photocatalysis of TiO(2)-B@anatase NWs for the removal of contamination from titanium surfaces has the potential to enable the rapid and complete establishment of early osseointegration. |
format | Online Article Text |
id | pubmed-7719464 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-77194642020-12-08 The Cleaning Effect of the Photocatalysis of TiO(2)-B@anatase Nanowires on Biological Activity on a Titanium Surface Gao, Yan Lin, Xi Zhao, Yadong Xu, Shulan Lai, Chunhua Guo, Zehong Wu, Wangxi Ding, Xianglong Jia, Fang Zhou, Lei Liu, Ying Int J Nanomedicine Original Research BACKGROUND: Improvements in the early osseointegration of titanium implants require investigations on the bone-implant interface, which is a critical and complex challenge. The surface cleanliness of titanium implants plays an important role at this interface. However, the implant surface would inevitably absorb contamination such as organic hydrocarbons, which is not conductive to the establishment of early osseointegration. Herein, an optimized approach for removing contamination from titanium surfaces was studied. METHODS: The TiO(2)-B@anatase NWs (nanowires) were prepared on titanium substrates through a hydrothermal process. A methylene blue degradation experiment was performed to assess the photodegradation activity. The cleaning effect of the photocatalysis of TiO(2)-B@anatase NWs on a titanium surface and the cellular early response was determined by analyzing cell morphology, attachment, proliferation and differentiation. RESULTS: The results indicated that the photocatalysis of TiO(2)-B@anatase NWs could effectively remove hydrocarbons on titanium surfaces without sacrificing the favourable titanium surface morphology. The methylene blue degradation experiment revealed that the photocatalysis of TiO(2)-B@anatase NWs had powerful degradation activity, which is attributed to the presence of strong oxidants such as (·)OH. In addition, compared to the merely ultraviolet-treated titanium surfaces, the titanium surfaces treated after the NWs photocatalytic cleaning process markedly enhanced cellular early response. CONCLUSION: The photocatalysis of TiO(2)-B@anatase NWs for the removal of contamination from titanium surfaces has the potential to enable the rapid and complete establishment of early osseointegration. Dove 2020-12-02 /pmc/articles/PMC7719464/ /pubmed/33299309 http://dx.doi.org/10.2147/IJN.S275373 Text en © 2020 Gao et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Gao, Yan Lin, Xi Zhao, Yadong Xu, Shulan Lai, Chunhua Guo, Zehong Wu, Wangxi Ding, Xianglong Jia, Fang Zhou, Lei Liu, Ying The Cleaning Effect of the Photocatalysis of TiO(2)-B@anatase Nanowires on Biological Activity on a Titanium Surface |
title | The Cleaning Effect of the Photocatalysis of TiO(2)-B@anatase Nanowires on Biological Activity on a Titanium Surface |
title_full | The Cleaning Effect of the Photocatalysis of TiO(2)-B@anatase Nanowires on Biological Activity on a Titanium Surface |
title_fullStr | The Cleaning Effect of the Photocatalysis of TiO(2)-B@anatase Nanowires on Biological Activity on a Titanium Surface |
title_full_unstemmed | The Cleaning Effect of the Photocatalysis of TiO(2)-B@anatase Nanowires on Biological Activity on a Titanium Surface |
title_short | The Cleaning Effect of the Photocatalysis of TiO(2)-B@anatase Nanowires on Biological Activity on a Titanium Surface |
title_sort | cleaning effect of the photocatalysis of tio(2)-b@anatase nanowires on biological activity on a titanium surface |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719464/ https://www.ncbi.nlm.nih.gov/pubmed/33299309 http://dx.doi.org/10.2147/IJN.S275373 |
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