A Rare, Unreported Cognitive Side Effect of Topiramate: Do We Know It All Yet?

This report describes a unique, dose dependent side effect of a commonly used drug, topiramate. Although cognitive side effects of this drug have previously been reported in literature, we present a case of drug-induced amnesia, with support from Naranjo Nomogram, as a hitherto unreported side effec...

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Detalles Bibliográficos
Autores principales: Karim, Nurose, Sheikh, Ajaz A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719466/
https://www.ncbi.nlm.nih.gov/pubmed/33304678
http://dx.doi.org/10.7759/cureus.11342
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author Karim, Nurose
Sheikh, Ajaz A
author_facet Karim, Nurose
Sheikh, Ajaz A
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description This report describes a unique, dose dependent side effect of a commonly used drug, topiramate. Although cognitive side effects of this drug have previously been reported in literature, we present a case of drug-induced amnesia, with support from Naranjo Nomogram, as a hitherto unreported side effect of topiramate. Here, we highlight the importance of being cognizant of such rare cognitive side effects, with the aim of improving patient outcome by timely recognition, and discontinuation of the offending drug, as the side effect was fortunately found to be reversible.
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spelling pubmed-77194662020-12-09 A Rare, Unreported Cognitive Side Effect of Topiramate: Do We Know It All Yet? Karim, Nurose Sheikh, Ajaz A Cureus Neurology This report describes a unique, dose dependent side effect of a commonly used drug, topiramate. Although cognitive side effects of this drug have previously been reported in literature, we present a case of drug-induced amnesia, with support from Naranjo Nomogram, as a hitherto unreported side effect of topiramate. Here, we highlight the importance of being cognizant of such rare cognitive side effects, with the aim of improving patient outcome by timely recognition, and discontinuation of the offending drug, as the side effect was fortunately found to be reversible. Cureus 2020-11-05 /pmc/articles/PMC7719466/ /pubmed/33304678 http://dx.doi.org/10.7759/cureus.11342 Text en Copyright © 2020, Karim et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Karim, Nurose
Sheikh, Ajaz A
A Rare, Unreported Cognitive Side Effect of Topiramate: Do We Know It All Yet?
title A Rare, Unreported Cognitive Side Effect of Topiramate: Do We Know It All Yet?
title_full A Rare, Unreported Cognitive Side Effect of Topiramate: Do We Know It All Yet?
title_fullStr A Rare, Unreported Cognitive Side Effect of Topiramate: Do We Know It All Yet?
title_full_unstemmed A Rare, Unreported Cognitive Side Effect of Topiramate: Do We Know It All Yet?
title_short A Rare, Unreported Cognitive Side Effect of Topiramate: Do We Know It All Yet?
title_sort rare, unreported cognitive side effect of topiramate: do we know it all yet?
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719466/
https://www.ncbi.nlm.nih.gov/pubmed/33304678
http://dx.doi.org/10.7759/cureus.11342
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