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Binary Political Optimizer for Feature Selection Using Gene Expression Data

DNA Microarray technology is an emergent field, which offers the possibility of obtaining simultaneous estimates of the expression levels of several thousand genes in an organism in a single experiment. One of the most significant challenges in this research field is to select high relevant genes fr...

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Detalles Bibliográficos
Autores principales: Manita, Ghaith, Korbaa, Ouajdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719494/
https://www.ncbi.nlm.nih.gov/pubmed/33312193
http://dx.doi.org/10.1155/2020/8896570
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author Manita, Ghaith
Korbaa, Ouajdi
author_facet Manita, Ghaith
Korbaa, Ouajdi
author_sort Manita, Ghaith
collection PubMed
description DNA Microarray technology is an emergent field, which offers the possibility of obtaining simultaneous estimates of the expression levels of several thousand genes in an organism in a single experiment. One of the most significant challenges in this research field is to select high relevant genes from gene expression data. To address this problem, feature selection is a well-known technique to eliminate unnecessary genes in order to ensure accurate classification results. This paper proposes a binary version of Political Optimizer (PO) to solve feature selection problem using gene expression data. Two transfer functions are used to design a binary PO. The first one is based on Sigmoid function and will be noted as BPO-S, while the second one is based on V-shaped function and will be noted as BPO-V. The proposed methods are evaluated using 9 biological datasets and compared with 8 binary well-known metaheuristics. The comparative results show the prevalent performance of the BPO methods especially BPO-V in comparison with other techniques.
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spelling pubmed-77194942020-12-11 Binary Political Optimizer for Feature Selection Using Gene Expression Data Manita, Ghaith Korbaa, Ouajdi Comput Intell Neurosci Research Article DNA Microarray technology is an emergent field, which offers the possibility of obtaining simultaneous estimates of the expression levels of several thousand genes in an organism in a single experiment. One of the most significant challenges in this research field is to select high relevant genes from gene expression data. To address this problem, feature selection is a well-known technique to eliminate unnecessary genes in order to ensure accurate classification results. This paper proposes a binary version of Political Optimizer (PO) to solve feature selection problem using gene expression data. Two transfer functions are used to design a binary PO. The first one is based on Sigmoid function and will be noted as BPO-S, while the second one is based on V-shaped function and will be noted as BPO-V. The proposed methods are evaluated using 9 biological datasets and compared with 8 binary well-known metaheuristics. The comparative results show the prevalent performance of the BPO methods especially BPO-V in comparison with other techniques. Hindawi 2020-11-29 /pmc/articles/PMC7719494/ /pubmed/33312193 http://dx.doi.org/10.1155/2020/8896570 Text en Copyright © 2020 Ghaith Manita and Ouajdi Korbaa. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Manita, Ghaith
Korbaa, Ouajdi
Binary Political Optimizer for Feature Selection Using Gene Expression Data
title Binary Political Optimizer for Feature Selection Using Gene Expression Data
title_full Binary Political Optimizer for Feature Selection Using Gene Expression Data
title_fullStr Binary Political Optimizer for Feature Selection Using Gene Expression Data
title_full_unstemmed Binary Political Optimizer for Feature Selection Using Gene Expression Data
title_short Binary Political Optimizer for Feature Selection Using Gene Expression Data
title_sort binary political optimizer for feature selection using gene expression data
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719494/
https://www.ncbi.nlm.nih.gov/pubmed/33312193
http://dx.doi.org/10.1155/2020/8896570
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