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Which Factors Affect the Occurrence of Off-Target Effects Caused by the Use of CRISPR/Cas: A Systematic Review in Plants
CRISPR/Cas enables a targeted modification of DNA sequences. Despite their ease and efficient use, one limitation is the potential occurrence of associated off-target effects. This systematic review aims to answer the following research question: Which factors affect the occurrence of off-target eff...
Autores principales: | Modrzejewski, Dominik, Hartung, Frank, Lehnert, Heike, Sprink, Thorben, Kohl, Christian, Keilwagen, Jens, Wilhelm, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719684/ https://www.ncbi.nlm.nih.gov/pubmed/33329634 http://dx.doi.org/10.3389/fpls.2020.574959 |
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