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Erythroid Differentiation and Heme Biosynthesis Are Dependent on a Shift in the Balance of Mitochondrial Fusion and Fission Dynamics
Erythropoiesis is the most robust cellular differentiation and proliferation system, with a production of ∼2 × 10(11) cells per day. In this fine-tuned process, the hematopoietic stem cells (HSCs) generate erythroid progenitors, which proliferate and mature into erythrocytes. During erythropoiesis,...
Autores principales: | Gonzalez-Ibanez, Alvaro M., Ruiz, Lina M., Jensen, Erik, Echeverria, Cesar A., Romero, Valentina, Stiles, Linsey, Shirihai, Orian S., Elorza, Alvaro A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719720/ https://www.ncbi.nlm.nih.gov/pubmed/33330472 http://dx.doi.org/10.3389/fcell.2020.592035 |
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