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Tm7sf2 Disruption Alters Radial Gene Positioning in Mouse Liver Leading to Metabolic Defects and Diabetes Characteristics

Tissue-specific patterns of radial genome organization contribute to genome regulation and can be established by nuclear envelope proteins. Studies in this area often use cancer cell lines, and it is unclear how well such systems recapitulate genome organization of primary cells or animal tissues; s...

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Detalles Bibliográficos
Autores principales:	Gatticchi, Leonardo, de las Heras, Jose I., Sivakumar, Aishwarya, Zuleger, Nikolaj, Roberti, Rita, Schirmer, Eric C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719783/ https://www.ncbi.nlm.nih.gov/pubmed/33330474 http://dx.doi.org/10.3389/fcell.2020.592573

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