Proteasome-Mediated Regulation of Cdhr1a by Siah1 Modulates Photoreceptor Development and Survival in Zebrafish

Congenital retinal dystrophies are a major cause of unpreventable and incurable blindness worldwide. Mutations in CDHR1, a retina specific cadherin, are associated with cone-rod dystrophy. The ubiquitin proteasome system (UPS) is responsible for mediating orderly and precise targeting of protein deg...

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Detalles Bibliográficos
Autores principales: Piedade, Warlen Pereira, Titialii-Torres, Kayla, Morris, Ann C., Famulski, Jakub K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719784/
https://www.ncbi.nlm.nih.gov/pubmed/33330480
http://dx.doi.org/10.3389/fcell.2020.594290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719784/
https://www.ncbi.nlm.nih.gov/pubmed/33330480
http://dx.doi.org/10.3389/fcell.2020.594290

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