Novel Non-Coding Transcript in NR4A3 Locus, LncNR4A3, Regulates RNA Processing Machinery Proteins and NR4A3 Expression

NR4A3 is a key tumor suppressor in myeloid malignancy, mice lacking both NR4A1 and family member NR4A3 rapidly develop lethal acute myeloid leukemia (AML). We identified a long non-coding transcript in the NR4A3 locus and pursued the characterization of this anonymous transcript and the study of its...

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Detalles Bibliográficos
Autores principales: Congrains, Ada, Niemann, Fernanda Soares, Duarte, Adriana Da Silva Santos, Ferro, Karla Priscila Vieira, Olalla-Saad, Sara Teresinha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719789/
https://www.ncbi.nlm.nih.gov/pubmed/33330042
http://dx.doi.org/10.3389/fonc.2020.569668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719789/
https://www.ncbi.nlm.nih.gov/pubmed/33330042
http://dx.doi.org/10.3389/fonc.2020.569668

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