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Novel Non-Coding Transcript in NR4A3 Locus, LncNR4A3, Regulates RNA Processing Machinery Proteins and NR4A3 Expression
NR4A3 is a key tumor suppressor in myeloid malignancy, mice lacking both NR4A1 and family member NR4A3 rapidly develop lethal acute myeloid leukemia (AML). We identified a long non-coding transcript in the NR4A3 locus and pursued the characterization of this anonymous transcript and the study of its...
Autores principales: | Congrains, Ada, Niemann, Fernanda Soares, Duarte, Adriana Da Silva Santos, Ferro, Karla Priscila Vieira, Olalla-Saad, Sara Teresinha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719789/ https://www.ncbi.nlm.nih.gov/pubmed/33330042 http://dx.doi.org/10.3389/fonc.2020.569668 |
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