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Paired Rheumatoid Arthritis Synovial Biopsies From Small and Large Joints Show Similar Global Transcriptomic Patterns With Enrichment of Private Specificity TCRB and TCR Signaling Pathways
OBJECTIVES: We explored histological and transcriptomic profiles of paired synovial biopsies from rheumatoid arthritis (RA) patients, in order to assess homogeneity in synovial tissue at the individual level. METHODS: Synovial biopsies were performed simultaneously in one small and one large joint p...
Autores principales: | Triaille, Clement, Vansteenkiste, Louise, Constant, Manuel, Ambroise, Jérôme, Méric de Bellefon, Laurent, Nzeusseu Toukap, Adrien, Sokolova, Tatiana, Galant, Christine, Coulie, Pierre, Carrasco, Javier, Durez, Patrick, Lauwerys, Bernard R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719799/ https://www.ncbi.nlm.nih.gov/pubmed/33329580 http://dx.doi.org/10.3389/fimmu.2020.593083 |
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