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Development of Improved Mumps Vaccine Candidates by Mutating Viral mRNA Cap Methyltransferase Sites in the Large Polymerase Protein

Although a live attenuated vaccine is available for controlling mumps virus (MuV), mumps still outbreaks frequently worldwide. The attenuated MuV vaccine strain S79 is widely used in mumps vaccination in China, but still with many shortcomings, among which the most prominent are the side effects and...

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Detalles Bibliográficos
Autores principales: Hao, Xiaoqiang, Wang, Yilong, Zhu, Mengying, Zhou, Dongming, Liu, Rongxian, Wang, Bin, Huang, Yao-Wei, Zhao, Zhengyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719854/
https://www.ncbi.nlm.nih.gov/pubmed/33284397
http://dx.doi.org/10.1007/s12250-020-00326-y