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Application of Bacillus subtilis as a live vaccine vector: A review
Bacillus subtilis is widely used as a probiotic in various fields as it regulates intestinal flora, improves animal growth performance, enhances body immunity, has short fermentation cycle, and is economic. With the rapid development of DNA recombination technology, B. subtilis has been used as a po...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Veterinary Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719876/ https://www.ncbi.nlm.nih.gov/pubmed/33071249 http://dx.doi.org/10.1292/jvms.20-0363 |
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author | LV, Penghao SONG, Yanying LIU, Cong YU, Lanping SHANG, Yingli TANG, Hui SUN, Shuhong WANG, Fangkun |
author_facet | LV, Penghao SONG, Yanying LIU, Cong YU, Lanping SHANG, Yingli TANG, Hui SUN, Shuhong WANG, Fangkun |
author_sort | LV, Penghao |
collection | PubMed |
description | Bacillus subtilis is widely used as a probiotic in various fields as it regulates intestinal flora, improves animal growth performance, enhances body immunity, has short fermentation cycle, and is economic. With the rapid development of DNA recombination technology, B. subtilis has been used as a potential vaccine expression vector for the treatment and prevention of various diseases caused by bacteria, viruses, and parasites as it can effectively trigger an immune response in the body. In this review, we refer to previous literature and provide a comprehensive analysis and overview of the feasibility of using B. subtilis as a vaccine expression vector, with an aim to provide a valuable reference for the establishment of efficient vaccines. |
format | Online Article Text |
id | pubmed-7719876 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Japanese Society of Veterinary Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-77198762020-12-09 Application of Bacillus subtilis as a live vaccine vector: A review LV, Penghao SONG, Yanying LIU, Cong YU, Lanping SHANG, Yingli TANG, Hui SUN, Shuhong WANG, Fangkun J Vet Med Sci Immunology Bacillus subtilis is widely used as a probiotic in various fields as it regulates intestinal flora, improves animal growth performance, enhances body immunity, has short fermentation cycle, and is economic. With the rapid development of DNA recombination technology, B. subtilis has been used as a potential vaccine expression vector for the treatment and prevention of various diseases caused by bacteria, viruses, and parasites as it can effectively trigger an immune response in the body. In this review, we refer to previous literature and provide a comprehensive analysis and overview of the feasibility of using B. subtilis as a vaccine expression vector, with an aim to provide a valuable reference for the establishment of efficient vaccines. The Japanese Society of Veterinary Science 2020-10-16 2020-11 /pmc/articles/PMC7719876/ /pubmed/33071249 http://dx.doi.org/10.1292/jvms.20-0363 Text en ©2020 The Japanese Society of Veterinary Science This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Immunology LV, Penghao SONG, Yanying LIU, Cong YU, Lanping SHANG, Yingli TANG, Hui SUN, Shuhong WANG, Fangkun Application of Bacillus subtilis as a live vaccine vector: A review |
title | Application of Bacillus subtilis as a live vaccine vector: A review |
title_full | Application of Bacillus subtilis as a live vaccine vector: A review |
title_fullStr | Application of Bacillus subtilis as a live vaccine vector: A review |
title_full_unstemmed | Application of Bacillus subtilis as a live vaccine vector: A review |
title_short | Application of Bacillus subtilis as a live vaccine vector: A review |
title_sort | application of bacillus subtilis as a live vaccine vector: a review |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719876/ https://www.ncbi.nlm.nih.gov/pubmed/33071249 http://dx.doi.org/10.1292/jvms.20-0363 |
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