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Maternal obesity persistently alters cardiac progenitor gene expression and programs adult-onset heart disease susceptibility

OBJECTIVE: Heart disease risk can be programmed by intrauterine exposure to obesity. Dysregulating key transcription factors in cardiac progenitors can cause subsequent adult-onset heart disease. In this study, we investigated the transcriptional pathways that are altered in the embryonic heart and...

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Detalles Bibliográficos
Autores principales:	Ahmed, Abdalla, Liang, Minggao, Chi, Lijun, Zhou, Yu-Qing, Sled, John G., Wilson, Michael D., Delgado-Olguín, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720025/ https://www.ncbi.nlm.nih.gov/pubmed/33212270 http://dx.doi.org/10.1016/j.molmet.2020.101116

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