Systematic mapping of cancer cell target dependencies using high-throughput drug screening in triple-negative breast cancer

While high-throughput drug screening offers possibilities to profile phenotypic responses of hundreds of compounds, elucidation of the cell context-specific mechanisms of drug action requires additional analyses. To that end, we developed a computational target deconvolution pipeline that identifies...

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Detalles Bibliográficos
Autores principales: Wang, Tianduanyi, Gautam, Prson, Rousu, Juho, Aittokallio, Tero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720026/
https://www.ncbi.nlm.nih.gov/pubmed/33335681
http://dx.doi.org/10.1016/j.csbj.2020.11.001

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