Unbiased in vivo preclinical evaluation of anticancer drugs identifies effective therapy for the treatment of pancreatic adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is typically diagnosed at an advanced stage, which limits surgical options and portends a dismal prognosis. Current oncologic PDAC therapies confer marginal benefit and, thus, a significant unmet clinical need exists for new therapeutic strategies. To identify...

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Detalles Bibliográficos
Autores principales: Grbovic-Huezo, Olivera, Pitter, Kenneth L., Lecomte, Nicolas, Saglimbeni, Joseph, Askan, Gokce, Holm, Matilda, Melchor, Jerry P., Chandwani, Rohit, Joshi, Suhasini, Haglund, Caj, Iacobuzio-Donahue, Christine A., Chiosis, Gabriela, Tammela, Tuomas, Leach, Steven D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720119/
https://www.ncbi.nlm.nih.gov/pubmed/33199632
http://dx.doi.org/10.1073/pnas.1920240117

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