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Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data
AIM: To evaluate overall survival (OS), glycemic control in cancer patients with and without diabetes mellitus (DM). PATIENTS & METHODS: Patients (2010–2015) with newly diagnosed prostate, breast, lung, colorectal and pancreatic cancers were identified in institutional cancer registry. Data link...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Science Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720374/ https://www.ncbi.nlm.nih.gov/pubmed/33312702 http://dx.doi.org/10.2144/fsoa-2020-0055 |
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author | Karlin, Nina J Buras, Matthew R Kosiorek, Heidi E Coppola, Kyle E Verona, Patricia M Cook, Curtiss B |
author_facet | Karlin, Nina J Buras, Matthew R Kosiorek, Heidi E Coppola, Kyle E Verona, Patricia M Cook, Curtiss B |
author_sort | Karlin, Nina J |
collection | PubMed |
description | AIM: To evaluate overall survival (OS), glycemic control in cancer patients with and without diabetes mellitus (DM). PATIENTS & METHODS: Patients (2010–2015) with newly diagnosed prostate, breast, lung, colorectal and pancreatic cancers were identified in institutional cancer registry. Data linked to National Death Index for vital status. 5-year OS estimated; glucose and hemoglobin A(1c) assessed during year postdiagnosis. RESULTS: We identified 1404 patients (non-DM, n = 936; DM, n = 468). DM cohort had 168 deaths (36%); non-DM, 267 (29%). 5-year OS estimated at 58% (95% CI: 53–64%) for DM and 67% (95% CI: 64–71%) for controls; for matched pairs, hazard ratio: 1.35 (95% CI: 1.02–1.79). Cancer did not harm glycemic control. CONCLUSION: OS among cancer patients with DM was lower than without DM. |
format | Online Article Text |
id | pubmed-7720374 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Future Science Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-77203742020-12-11 Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data Karlin, Nina J Buras, Matthew R Kosiorek, Heidi E Coppola, Kyle E Verona, Patricia M Cook, Curtiss B Future Sci OA Research Article AIM: To evaluate overall survival (OS), glycemic control in cancer patients with and without diabetes mellitus (DM). PATIENTS & METHODS: Patients (2010–2015) with newly diagnosed prostate, breast, lung, colorectal and pancreatic cancers were identified in institutional cancer registry. Data linked to National Death Index for vital status. 5-year OS estimated; glucose and hemoglobin A(1c) assessed during year postdiagnosis. RESULTS: We identified 1404 patients (non-DM, n = 936; DM, n = 468). DM cohort had 168 deaths (36%); non-DM, 267 (29%). 5-year OS estimated at 58% (95% CI: 53–64%) for DM and 67% (95% CI: 64–71%) for controls; for matched pairs, hazard ratio: 1.35 (95% CI: 1.02–1.79). Cancer did not harm glycemic control. CONCLUSION: OS among cancer patients with DM was lower than without DM. Future Science Ltd 2020-10-20 /pmc/articles/PMC7720374/ /pubmed/33312702 http://dx.doi.org/10.2144/fsoa-2020-0055 Text en © 2020 Mayo Foundation for Medical Education and Research This work is licensed under the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/) |
spellingShingle | Research Article Karlin, Nina J Buras, Matthew R Kosiorek, Heidi E Coppola, Kyle E Verona, Patricia M Cook, Curtiss B Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data |
title | Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data |
title_full | Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data |
title_fullStr | Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data |
title_full_unstemmed | Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data |
title_short | Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data |
title_sort | assessing the relationship between institutional cancer and diabetes mortality rates using national death index data |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720374/ https://www.ncbi.nlm.nih.gov/pubmed/33312702 http://dx.doi.org/10.2144/fsoa-2020-0055 |
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