Cargando…

Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data

AIM: To evaluate overall survival (OS), glycemic control in cancer patients with and without diabetes mellitus (DM). PATIENTS & METHODS: Patients (2010–2015) with newly diagnosed prostate, breast, lung, colorectal and pancreatic cancers were identified in institutional cancer registry. Data link...

Descripción completa

Detalles Bibliográficos
Autores principales: Karlin, Nina J, Buras, Matthew R, Kosiorek, Heidi E, Coppola, Kyle E, Verona, Patricia M, Cook, Curtiss B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720374/
https://www.ncbi.nlm.nih.gov/pubmed/33312702
http://dx.doi.org/10.2144/fsoa-2020-0055
_version_ 1783619838806065152
author Karlin, Nina J
Buras, Matthew R
Kosiorek, Heidi E
Coppola, Kyle E
Verona, Patricia M
Cook, Curtiss B
author_facet Karlin, Nina J
Buras, Matthew R
Kosiorek, Heidi E
Coppola, Kyle E
Verona, Patricia M
Cook, Curtiss B
author_sort Karlin, Nina J
collection PubMed
description AIM: To evaluate overall survival (OS), glycemic control in cancer patients with and without diabetes mellitus (DM). PATIENTS & METHODS: Patients (2010–2015) with newly diagnosed prostate, breast, lung, colorectal and pancreatic cancers were identified in institutional cancer registry. Data linked to National Death Index for vital status. 5-year OS estimated; glucose and hemoglobin A(1c) assessed during year postdiagnosis. RESULTS: We identified 1404 patients (non-DM, n = 936; DM, n = 468). DM cohort had 168 deaths (36%); non-DM, 267 (29%). 5-year OS estimated at 58% (95% CI: 53–64%) for DM and 67% (95% CI: 64–71%) for controls; for matched pairs, hazard ratio: 1.35 (95% CI: 1.02–1.79). Cancer did not harm glycemic control. CONCLUSION: OS among cancer patients with DM was lower than without DM.
format Online
Article
Text
id pubmed-7720374
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Future Science Ltd
record_format MEDLINE/PubMed
spelling pubmed-77203742020-12-11 Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data Karlin, Nina J Buras, Matthew R Kosiorek, Heidi E Coppola, Kyle E Verona, Patricia M Cook, Curtiss B Future Sci OA Research Article AIM: To evaluate overall survival (OS), glycemic control in cancer patients with and without diabetes mellitus (DM). PATIENTS & METHODS: Patients (2010–2015) with newly diagnosed prostate, breast, lung, colorectal and pancreatic cancers were identified in institutional cancer registry. Data linked to National Death Index for vital status. 5-year OS estimated; glucose and hemoglobin A(1c) assessed during year postdiagnosis. RESULTS: We identified 1404 patients (non-DM, n = 936; DM, n = 468). DM cohort had 168 deaths (36%); non-DM, 267 (29%). 5-year OS estimated at 58% (95% CI: 53–64%) for DM and 67% (95% CI: 64–71%) for controls; for matched pairs, hazard ratio: 1.35 (95% CI: 1.02–1.79). Cancer did not harm glycemic control. CONCLUSION: OS among cancer patients with DM was lower than without DM. Future Science Ltd 2020-10-20 /pmc/articles/PMC7720374/ /pubmed/33312702 http://dx.doi.org/10.2144/fsoa-2020-0055 Text en © 2020 Mayo Foundation for Medical Education and Research This work is licensed under the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/)
spellingShingle Research Article
Karlin, Nina J
Buras, Matthew R
Kosiorek, Heidi E
Coppola, Kyle E
Verona, Patricia M
Cook, Curtiss B
Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data
title Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data
title_full Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data
title_fullStr Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data
title_full_unstemmed Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data
title_short Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data
title_sort assessing the relationship between institutional cancer and diabetes mortality rates using national death index data
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720374/
https://www.ncbi.nlm.nih.gov/pubmed/33312702
http://dx.doi.org/10.2144/fsoa-2020-0055
work_keys_str_mv AT karlinninaj assessingtherelationshipbetweeninstitutionalcanceranddiabetesmortalityratesusingnationaldeathindexdata
AT burasmatthewr assessingtherelationshipbetweeninstitutionalcanceranddiabetesmortalityratesusingnationaldeathindexdata
AT kosiorekheidie assessingtherelationshipbetweeninstitutionalcanceranddiabetesmortalityratesusingnationaldeathindexdata
AT coppolakylee assessingtherelationshipbetweeninstitutionalcanceranddiabetesmortalityratesusingnationaldeathindexdata
AT veronapatriciam assessingtherelationshipbetweeninstitutionalcanceranddiabetesmortalityratesusingnationaldeathindexdata
AT cookcurtissb assessingtherelationshipbetweeninstitutionalcanceranddiabetesmortalityratesusingnationaldeathindexdata