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Simplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance

BACKGROUND: An O-ring gantry-type linear accelerator (LINAC) with a 6-MV flattening filter-free (FFF) photon beam, Halcyon, includes a reference beam that contains representative information such as the percent depth dose, profile and output factor for commissioning and quality assurance. However, b...

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Autores principales: Choi, Min-Geon, Law, Martin, Yoon, Do-Kun, Tamura, Mikoto, Matsumoto, Kenji, Otsuka, Masakazu, Kim, Moo-Sub, Djeng, Shih-Kien, Monzen, Hajime, Suh, Tae Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720380/
https://www.ncbi.nlm.nih.gov/pubmed/33287828
http://dx.doi.org/10.1186/s13014-020-01709-x
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author Choi, Min-Geon
Law, Martin
Yoon, Do-Kun
Tamura, Mikoto
Matsumoto, Kenji
Otsuka, Masakazu
Kim, Moo-Sub
Djeng, Shih-Kien
Monzen, Hajime
Suh, Tae Suk
author_facet Choi, Min-Geon
Law, Martin
Yoon, Do-Kun
Tamura, Mikoto
Matsumoto, Kenji
Otsuka, Masakazu
Kim, Moo-Sub
Djeng, Shih-Kien
Monzen, Hajime
Suh, Tae Suk
author_sort Choi, Min-Geon
collection PubMed
description BACKGROUND: An O-ring gantry-type linear accelerator (LINAC) with a 6-MV flattening filter-free (FFF) photon beam, Halcyon, includes a reference beam that contains representative information such as the percent depth dose, profile and output factor for commissioning and quality assurance. However, because it does not provide information about the field size, we proposed a method to determine all field sizes according to all depths for radiation therapy using simplified sigmoidal curve fitting (SCF). METHODS: After mathematical definition of the SCF using four coefficients, the defined curves were fitted to both the reference data (RD) and the measured data (MD). For good agreement between the fitting curve and the profiles in each data set, the field sizes were determined by identifying the maximum point along the third derivative of the fitting curve. The curve fitting included the field sizes for beam profiles of 2 × 2, 4 × 4, 6 × 6, 8 × 8, 10 × 10, 20 × 20 and 28 × 28 cm(2) as a function of depth (at 1.3, 5, 10 and 20 cm). The field size results from the RD were compared with the results from the MD using the same condition. RESULTS: All fitting curves show goodness of fit, R(2), values that are greater than 0.99. The differences in field size between the RD and the MD were within the range of 0 to 0.2 cm. The smallest difference in the field sizes at a depth of 10 cm, which is a surface-to-axis distance, was reported. CONCLUSION: Application of the SCF method has been proven to accurately capture the field size of the preconfigured RD and the measured FFF photon beam data for the Halcyon system. The current work can be useful for beam commissioning as a countercheck methodology to determine the field size from RD in the treatment planning system of a newly installed Halcyon system and for routine quality assurance to ascertain the correctness of field sizes for clinical use of the Halcyon system.
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spelling pubmed-77203802020-12-07 Simplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance Choi, Min-Geon Law, Martin Yoon, Do-Kun Tamura, Mikoto Matsumoto, Kenji Otsuka, Masakazu Kim, Moo-Sub Djeng, Shih-Kien Monzen, Hajime Suh, Tae Suk Radiat Oncol Research BACKGROUND: An O-ring gantry-type linear accelerator (LINAC) with a 6-MV flattening filter-free (FFF) photon beam, Halcyon, includes a reference beam that contains representative information such as the percent depth dose, profile and output factor for commissioning and quality assurance. However, because it does not provide information about the field size, we proposed a method to determine all field sizes according to all depths for radiation therapy using simplified sigmoidal curve fitting (SCF). METHODS: After mathematical definition of the SCF using four coefficients, the defined curves were fitted to both the reference data (RD) and the measured data (MD). For good agreement between the fitting curve and the profiles in each data set, the field sizes were determined by identifying the maximum point along the third derivative of the fitting curve. The curve fitting included the field sizes for beam profiles of 2 × 2, 4 × 4, 6 × 6, 8 × 8, 10 × 10, 20 × 20 and 28 × 28 cm(2) as a function of depth (at 1.3, 5, 10 and 20 cm). The field size results from the RD were compared with the results from the MD using the same condition. RESULTS: All fitting curves show goodness of fit, R(2), values that are greater than 0.99. The differences in field size between the RD and the MD were within the range of 0 to 0.2 cm. The smallest difference in the field sizes at a depth of 10 cm, which is a surface-to-axis distance, was reported. CONCLUSION: Application of the SCF method has been proven to accurately capture the field size of the preconfigured RD and the measured FFF photon beam data for the Halcyon system. The current work can be useful for beam commissioning as a countercheck methodology to determine the field size from RD in the treatment planning system of a newly installed Halcyon system and for routine quality assurance to ascertain the correctness of field sizes for clinical use of the Halcyon system. BioMed Central 2020-12-07 /pmc/articles/PMC7720380/ /pubmed/33287828 http://dx.doi.org/10.1186/s13014-020-01709-x Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Choi, Min-Geon
Law, Martin
Yoon, Do-Kun
Tamura, Mikoto
Matsumoto, Kenji
Otsuka, Masakazu
Kim, Moo-Sub
Djeng, Shih-Kien
Monzen, Hajime
Suh, Tae Suk
Simplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance
title Simplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance
title_full Simplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance
title_fullStr Simplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance
title_full_unstemmed Simplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance
title_short Simplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance
title_sort simplified sigmoidal curve fitting for a 6 mv fff photon beam of the halcyon to determine the field size for beam commissioning and quality assurance
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720380/
https://www.ncbi.nlm.nih.gov/pubmed/33287828
http://dx.doi.org/10.1186/s13014-020-01709-x
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