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MicroRNA-302a is involved in folate deficiency-induced apoptosis through the AKT-FOXO1-BIM pathway in mouse embryonic stem cells

BACKGROUND: Our previous study had shown that microRNA (miR)-302a played a key role in folate deficiency-induced apoptosis in mouse embryonic stem cells. However, details regarding the mechanism remain unclear. Transcription factors (TFs) and miRNAs are two key elements in gene regulation. The aim o...

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Detalles Bibliográficos
Autores principales: Liang, Yan, Cao, Dingding, Li, Yuanyuan, Liu, Zhuo, Wu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720404/
https://www.ncbi.nlm.nih.gov/pubmed/33372619
http://dx.doi.org/10.1186/s12986-020-00530-3