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MicroRNA-302a is involved in folate deficiency-induced apoptosis through the AKT-FOXO1-BIM pathway in mouse embryonic stem cells
BACKGROUND: Our previous study had shown that microRNA (miR)-302a played a key role in folate deficiency-induced apoptosis in mouse embryonic stem cells. However, details regarding the mechanism remain unclear. Transcription factors (TFs) and miRNAs are two key elements in gene regulation. The aim o...
Autores principales: | Liang, Yan, Cao, Dingding, Li, Yuanyuan, Liu, Zhuo, Wu, Jianxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720404/ https://www.ncbi.nlm.nih.gov/pubmed/33372619 http://dx.doi.org/10.1186/s12986-020-00530-3 |
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