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Growth hormone activates PI3K/Akt signaling and inhibits ROS accumulation and apoptosis in granulosa cells of patients with polycystic ovary syndrome

BACKGROUND: It is reported that growth hormone (GH) can alleviate oxidative stress (OS) induced apoptosis in some types of cells by activating the PI3K/Akt signaling pathway. This study investigated the role and underlying mechanism of GH in OS and apoptosis in granulosa cells (GCs) of patients with...

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Detalles Bibliográficos
Autores principales:	Gong, Yan, Luo, Shan, Fan, Ping, Zhu, Huili, Li, Yujing, Huang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720521/ https://www.ncbi.nlm.nih.gov/pubmed/33287836 http://dx.doi.org/10.1186/s12958-020-00677-x

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