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Hyaluronic acid-coated polymeric micelles with hydrogen peroxide scavenging to encapsulate statins for alleviating atherosclerosis
Inflammation and oxidative stress are two major factors that are involved in the pathogenesis of atherosclerosis. A smart drug delivery system that responds to the oxidative microenvironment of atherosclerotic plaques was constructed in the present study. Simvastatin (SIM)-loaded biodegradable polym...
Autores principales: | Mu, Dan, Li, Jianhui, Qi, Yu, Sun, Xuan, Liu, Yihai, Shen, Song, Li, Yuyu, Xu, Biao, Zhang, Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720571/ https://www.ncbi.nlm.nih.gov/pubmed/33287831 http://dx.doi.org/10.1186/s12951-020-00744-w |
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