Rapid, high-yield production of full-length SARS-CoV-2 spike ectodomain by transient gene expression in CHO cells

Recombinant forms of the spike protein of SARS-CoV-2 and related viruses have proven difficult to produce with good yields in mammalian cells. Given the panoply of potential COVID-19 diagnostic tools and therapeutic candidates that require purified spike protein and its importance for ongoing SARS-C...

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Detalles Bibliográficos
Autores principales: Stuible, Matthew, Gervais, Christian, Lord-Dufour, Simon, Perret, Sylvie, L’Abbé, Denis, Schrag, Joseph, St-Laurent, Gilles, Durocher, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720734/
https://www.ncbi.nlm.nih.gov/pubmed/33301853
http://dx.doi.org/10.1016/j.jbiotec.2020.12.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720734/
https://www.ncbi.nlm.nih.gov/pubmed/33301853
http://dx.doi.org/10.1016/j.jbiotec.2020.12.005

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