Cargando…

Predictors of immunotherapy benefit in Merkel cell carcinoma

Merkel cell carcinoma is a rare cancer for which immune checkpoint blockade is standard-of-care for recurrent/metastatic disease. However, not all patients benefit from immunotherapy. A greater understanding of molecular mechanisms and predictive biomarkers are unmet needs. We retrospectively analyz...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kacew, Alec J., Dharaneeswaran, Harita, Starrett, Gabriel J., Thakuria, Manisha, LeBoeuf, Nicole R., Silk, Ann W., DeCaprio, James A., Hanna, Glenn J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720777/ https://www.ncbi.nlm.nih.gov/pubmed/33315984 http://dx.doi.org/10.18632/oncotarget.27823

Ejemplares similares

Association of Programmed Death 1 Protein Ligand (PD-L1) Expression With Prognosis in Merkel Cell Carcinoma
por: Hanna, Glenn J., et al.
Publicado: (2020)

YAP1 and WWTR1 expression inversely correlates with neuroendocrine markers in Merkel cell carcinoma
por: Frost, Thomas C., et al.
Publicado: (2023)

Real-world outcomes treating patients with advanced cutaneous squamous cell carcinoma with immune checkpoint inhibitors (CPI)
por: Hanna, Glenn J., et al.
Publicado: (2020)

Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell Carcinoma
por: Starrett, Gabriel J., et al.
Publicado: (2017)

Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma
por: Starrett, Gabriel J., et al.
Publicado: (2020)

Merkel Cell Polyomavirus: Oncogenesis in a Stable Genome
por: Ahmed, Mona M., et al.
Publicado: (2021)

Does a new polyomavirus contribute to Merkel cell carcinoma?
por: Garneski, Kelly M, et al.
Publicado: (2008)

Value and Unmet Needs in Non-Invasive Human Papillomavirus (HPV) Testing for Oropharyngeal Cancer
por: Kacew, Alec J., et al.
Publicado: (2021)

The Merkel Cell Polyomavirus T Antigens Function as Tumor Promoters in Murine Skin
por: Spurgeon, Megan E., et al.
Publicado: (2021)

The biology and treatment of Merkel cell carcinoma: current understanding and research priorities
por: Harms, Paul W., et al.
Publicado: (2018)

FGFR3 Alterations in the Era of Immunotherapy for Urothelial Bladder Cancer
por: Kacew, Alec, et al.
Publicado: (2020)

Integrative analysis reveals therapeutic potential of pyrvinium pamoate in Merkel cell carcinoma
por: Yang, Jiawen, et al.
Publicado: (2023)

Milademetan is a highly potent MDM2 inhibitor in Merkel cell carcinoma
por: Ananthapadmanabhan, Varsha, et al.
Publicado: (2022)

Merkel cell polyomavirus large T antigen binding to pRb promotes skin hyperplasia and tumor development
por: Spurgeon, Megan E., et al.
Publicado: (2022)

Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma
por: Lee, Patrick C., et al.
Publicado: (2022)

An analysis of the use of targeted therapies in patients with advanced Merkel cell carcinoma and an evaluation of genomic correlates of response
por: Knepper, Todd C., et al.
Publicado: (2021)

Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation
por: Berrios, Christian, et al.
Publicado: (2016)

Long-read sequencing reveals complex patterns of wraparound transcription in polyomaviruses
por: Nomburg, Jason, et al.
Publicado: (2022)

Merkel Cell Carcinoma: An Update and Immunotherapy
por: Uchi, Hiroshi
Publicado: (2018)

Immunotherapy in Merkel cell carcinoma: role of Avelumab
por: Palla, Amruth R, et al.
Publicado: (2018)

Merkel Cell Carcinoma: An Immunotherapy Fairy-Tale?
por: Tanda, Enrica Teresa, et al.
Publicado: (2021)

Addiction of Merkel cell carcinoma to MUC1-C identifies a potential new target for treatment
por: Morimoto, Yoshihiro, et al.
Publicado: (2022)

Immunotherapy for Merkel cell carcinoma: a turning point in patient care
por: Chan, Isaac S., et al.
Publicado: (2018)

Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis
por: Cheng, Jingwei, et al.
Publicado: (2017)

An Updated Review of the Biomarkers of Response to Immune Checkpoint Inhibitors in Merkel Cell Carcinoma: Merkel Cell Carcinoma and Immunotherapy
por: Fojnica, Adnan, et al.
Publicado: (2023)

Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis
por: Park, Donglim Esther, et al.
Publicado: (2020)

Burning pain on the upper labial mucosa
por: Fay, Christopher J., et al.
Publicado: (2023)

Tumor-specific T cells in human Merkel cell carcinomas: a possible role for Tregs and T cell exhaustion in reducing T cell responses
por: Dowlatshahi, Mitra, et al.
Publicado: (2013)

Edema of the face and extremities secondary to pemetrexed
por: Doyle, Thomas, et al.
Publicado: (2023)

Merkel Cell Polyomavirus and Merkel Cell Carcinoma
por: Pietropaolo, Valeria, et al.
Publicado: (2020)

DETECTing Merkel Cell Polyomavirus in Merkel Tumors
por: Arora, Reety, et al.
Publicado: (2020)

Rescue of Immunotherapy-Refractory Metastatic Merkel Cell Carcinoma With Conventionally Fractionated Radiotherapy and Concurrent Pembrolizumab
por: Bloom, Brooke C., et al.
Publicado: (2019)

COVID-19 in a patient with advanced Merkel cell carcinoma receiving immunotherapy
por: da Costa, Cesar Martins, et al.
Publicado: (2020)

Outcome of patient with myasthenia gravis with the use of immunotherapy in metastatic Merkel cell carcinoma
por: Williams, Sarah, et al.
Publicado: (2022)

Circulating tumor cell analysis in locally advanced and metastatic squamous cell carcinoma of the head and neck
por: Harris, Ethan J., et al.
Publicado: (2020)

Merkel cell carcinoma
por: Mistry, K., et al.
Publicado: (2021)

Merkel Cell Polyomavirus and Merkel Cell Carcinoma, France
por: Foulongne, Vincent, et al.
Publicado: (2008)

Merkel cell polyomavirus and cutaneous Merkel cell carcinoma
por: Minutilli, Ettore, et al.
Publicado: (2016)

Merkel cell polyomavirus and associated Merkel cell carcinoma
por: Yang, June F., et al.
Publicado: (2021)

Association of Merkel Cell Polyomavirus–Specific Antibodies With Merkel Cell Carcinoma
por: Carter, Joseph J., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_lsvcupam6lm8b9chki57bv4n8k