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Role of chromosomal instability and clonal heterogeneity in the therapy response of breast cancer cell lines

OBJECTIVE: Chromosomal instability (CIN) is a hallmark of cancer characterized by cell-to-cell variability in the number or structure of chromosomes, frequently observed in cancer cell populations and is associated with poor prognosis, metastasis, and therapeutic resistance. Breast cancer (BC) is ch...

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Detalles Bibliográficos
Autores principales: Vargas-Rondón, Natalia, Pérez-Mora, Erika, Villegas, Victoria E., Rondón-Lagos, Milena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721098/
https://www.ncbi.nlm.nih.gov/pubmed/33299647
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0028