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Role of chromosomal instability and clonal heterogeneity in the therapy response of breast cancer cell lines
OBJECTIVE: Chromosomal instability (CIN) is a hallmark of cancer characterized by cell-to-cell variability in the number or structure of chromosomes, frequently observed in cancer cell populations and is associated with poor prognosis, metastasis, and therapeutic resistance. Breast cancer (BC) is ch...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Compuscript
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721098/ https://www.ncbi.nlm.nih.gov/pubmed/33299647 http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0028 |