Cargando…

Role of chromosomal instability and clonal heterogeneity in the therapy response of breast cancer cell lines

OBJECTIVE: Chromosomal instability (CIN) is a hallmark of cancer characterized by cell-to-cell variability in the number or structure of chromosomes, frequently observed in cancer cell populations and is associated with poor prognosis, metastasis, and therapeutic resistance. Breast cancer (BC) is ch...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vargas-Rondón, Natalia, Pérez-Mora, Erika, Villegas, Victoria E., Rondón-Lagos, Milena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Compuscript 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721098/ https://www.ncbi.nlm.nih.gov/pubmed/33299647 http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0028

Ejemplares similares

The Role of Chromosomal Instability in Cancer and Therapeutic Responses
por: Vargas-Rondón, Natalia, et al.
Publicado: (2017)

Chromosomal Instability as Enabling Feature and Central Hallmark of Breast Cancer
por: Castellanos, Giovanny, et al.
Publicado: (2023)

New Insights in the Cytogenetic Practice: Karyotypic Chaos, Non-Clonal Chromosomal Alterations and Chromosomal Instability in Human Cancer and Therapy Response
por: Rangel, Nelson, et al.
Publicado: (2017)

Profile of Chromosomal Alterations, Chromosomal Instability and Clonal Heterogeneity in Colombian Farmers Exposed to Pesticides
por: Meléndez-Flórez, María Paula, et al.
Publicado: (2022)

Chromosomal Instability in Farmers Exposed to Pesticides: High Prevalence of Clonal and Non-Clonal Chromosomal Alterations
por: Cepeda, Sebastian, et al.
Publicado: (2020)

Resistance and Overcoming Resistance in Breast Cancer
por: Luque-Bolivar, Andrea, et al.
Publicado: (2020)

Profiling of gene expression regulated by 17β-estradiol and tamoxifen in estrogen receptor-positive and estrogen receptor-negative human breast cancer cell lines
por: Rangel, Nelson, et al.
Publicado: (2017)

Obesity and Androgen Receptor Signaling: Associations and Potential Crosstalk in Breast Cancer Cells
por: Rangel, Nelson, et al.
Publicado: (2021)

High chromosomal instability in workers occupationally exposed to solvents and paint removers
por: Villalba-Campos, Mónica, et al.
Publicado: (2016)

Intrinsic Subtypes and Androgen Receptor Gene Expression in Primary Breast Cancer. A Meta-Analysis
por: Cruz-Tapias, Paola, et al.
Publicado: (2021)

Analyzing biological and molecular characteristics and genomic damage induced by exposure to asbestos
por: Ospina, Diana, et al.
Publicado: (2019)

Tamoxifen Treatment of Breast Cancer Cells: Impact on Hedgehog/GLI1 Signaling
por: Villegas, Victoria E., et al.
Publicado: (2016)

Differences and homologies of chromosomal alterations within and between breast cancer cell lines: a clustering analysis
por: Rondón-Lagos, Milena, et al.
Publicado: (2014)

Tamoxifen Resistance: Emerging Molecular Targets
por: Rondón-Lagos, Milena, et al.
Publicado: (2016)

Unraveling the chromosome 17 patterns of FISH in interphase nuclei: an in-depth analysis of the HER2 amplicon and chromosome 17 centromere by karyotyping, FISH and M-FISH in breast cancer cells
por: Rondón-Lagos, Milena, et al.
Publicado: (2014)

Chinese hamster ovary cell line DXB-11: chromosomal instability and karyotype heterogeneity
por: Turilova, Victoria I., et al.
Publicado: (2021)

The role of clonal communication and heterogeneity in breast cancer
por: Martín-Pardillos, Ana, et al.
Publicado: (2019)

Affected chromosome homeostasis and genomic instability of clonal yeast cultures
por: Adamczyk, Jagoda, et al.
Publicado: (2015)

AR/ER Ratio Correlates with Expression of Proliferation Markers and with Distinct Subset of Breast Tumors
por: Rangel, Nelson, et al.
Publicado: (2020)

A Markov chain for numerical chromosomal instability in clonally expanding populations
por: Elizalde, Sergi, et al.
Publicado: (2018)

Disentangling the roles of aneuploidy, chromosomal instability and tumour heterogeneity in developing resistance to cancer therapies
por: Andrade, Joana Reis, et al.
Publicado: (2023)

Genetic heterogeneity and clonal evolution in neuroblastoma
por: Mora, J, et al.
Publicado: (2001)

Effect of low doses of estradiol and tamoxifen on breast cancer cell karyotypes
por: Rondón-Lagos, Milena, et al.
Publicado: (2016)

Clonal chromosomal and genomic instability during human multipotent mesenchymal stromal cells long-term culture
por: Nikitina, Victoria, et al.
Publicado: (2018)

Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy
por: Caswell-Jin, Jennifer L., et al.
Publicado: (2019)

Chromosomal instability and its effect on cell lines
por: He, Zichen, et al.
Publicado: (2023)

Detecting Chromosome Instability in Cancer: Approaches to Resolve Cell-to-Cell Heterogeneity
por: Lepage, Chloe C., et al.
Publicado: (2019)

Centrosome aberrations and chromosome instability contribute to tumorigenesis and intra-tumor heterogeneity
por: Jusino, Shirley, et al.
Publicado: (2018)

Publisher Correction: Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy
por: Caswell-Jin, Jennifer L., et al.
Publicado: (2019)

Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability
por: Salas-Armenteros, Irene, et al.
Publicado: (2019)

Chromosomal instability in the pathogenesis and treatment of breast cancer
por: Venkitaraman, A
Publicado: (2008)

Chromosomal instability in the lymphocytes of breast cancer patients
por: Harsimran, Kaur, et al.
Publicado: (2009)

Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer
por: Tucker, John B., et al.
Publicado: (2023)

Effectiveness of six molecular typing methods as epidemiological tools for the study of Salmonella isolates in two Colombian regions
por: Lozano-Villegas, Kelly, et al.
Publicado: (2019)

The Adaptability of Chromosomal Instability in Cancer Therapy and Resistance
por: Carloni, Vinicio, et al.
Publicado: (2022)

Chromosome-breakage genomic instability and chromothripsis in breast cancer
por: Przybytkowski, Ewa, et al.
Publicado: (2014)

Clonal analysis of a bladder cancer cell line: an experimental model of tumour heterogeneity.
por: Brown, J. L., et al.
Publicado: (1990)

Mathematical Modeling of Clonal Interference by Density-Dependent Selection in Heterogeneous Cancer Cell Lines
por: Veith, Thomas, et al.
Publicado: (2023)

Chromosomal Instability, Selection and Competition: Factors That Shape the Level of Karyotype Intra-Tumor Heterogeneity
por: van den Bosch, Tom, et al.
Publicado: (2022)

Biological and Clinical Implications of Clonal Heterogeneity and Clonal Evolution in Multiple Myeloma
por: Bianchi, Giada, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_13bgtc2emso0118hh6slir1uhh