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A dual-feedback loop model of the mammalian circadian clock for multi-input control of circadian phase
The molecular circadian clock is driven by interlocked transcriptional-translational feedback loops, producing oscillations in the expressions of genes and proteins to coordinate the timing of biological processes throughout the body. Modeling this system gives insight into the underlying processes...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721196/ https://www.ncbi.nlm.nih.gov/pubmed/33226977 http://dx.doi.org/10.1371/journal.pcbi.1008459 |