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Role of gut microbiota in metabolic syndrome: a review of recent evidence

The metabolic syndrome is a complex entity comprised of multiple cardiovascular risk factors grouped in a single individual, contributing to an increased rate of cardiovascular events which goes beyond what would be expected given the impact of each individual risk factor. It is a multifactorial con...

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Detalles Bibliográficos
Autores principales: Alveirinho, Manuel, Freitas, Paula, Faleiro, Maria Leonor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721214/
https://www.ncbi.nlm.nih.gov/pubmed/33299954
http://dx.doi.org/10.1097/j.pbj.0000000000000105
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author Alveirinho, Manuel
Freitas, Paula
Faleiro, Maria Leonor
author_facet Alveirinho, Manuel
Freitas, Paula
Faleiro, Maria Leonor
author_sort Alveirinho, Manuel
collection PubMed
description The metabolic syndrome is a complex entity comprised of multiple cardiovascular risk factors grouped in a single individual, contributing to an increased rate of cardiovascular events which goes beyond what would be expected given the impact of each individual risk factor. It is a multifactorial condition whose complete pathogenesis is not yet fully understood. Several studies have shown that not only the intestinal microbiota and dysbiosis may play a role in its pathogenesis, but also that modulating said microbiota may play a role in treating or at least ameliorating the metabolic syndrome. The purpose of this article is to review some of the most recent evidence linking the gut microbiome and the metabolic syndrome to help further understand this relationship and try to identify further research directions.
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spelling pubmed-77212142020-12-08 Role of gut microbiota in metabolic syndrome: a review of recent evidence Alveirinho, Manuel Freitas, Paula Faleiro, Maria Leonor Porto Biomed J Review Article The metabolic syndrome is a complex entity comprised of multiple cardiovascular risk factors grouped in a single individual, contributing to an increased rate of cardiovascular events which goes beyond what would be expected given the impact of each individual risk factor. It is a multifactorial condition whose complete pathogenesis is not yet fully understood. Several studies have shown that not only the intestinal microbiota and dysbiosis may play a role in its pathogenesis, but also that modulating said microbiota may play a role in treating or at least ameliorating the metabolic syndrome. The purpose of this article is to review some of the most recent evidence linking the gut microbiome and the metabolic syndrome to help further understand this relationship and try to identify further research directions. Lippincott Williams & Wilkins 2020-12-03 /pmc/articles/PMC7721214/ /pubmed/33299954 http://dx.doi.org/10.1097/j.pbj.0000000000000105 Text en Copyright © 2020 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of PBJ-Associação Porto Biomedical/Porto Biomedical Society. All rights reserved. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle Review Article
Alveirinho, Manuel
Freitas, Paula
Faleiro, Maria Leonor
Role of gut microbiota in metabolic syndrome: a review of recent evidence
title Role of gut microbiota in metabolic syndrome: a review of recent evidence
title_full Role of gut microbiota in metabolic syndrome: a review of recent evidence
title_fullStr Role of gut microbiota in metabolic syndrome: a review of recent evidence
title_full_unstemmed Role of gut microbiota in metabolic syndrome: a review of recent evidence
title_short Role of gut microbiota in metabolic syndrome: a review of recent evidence
title_sort role of gut microbiota in metabolic syndrome: a review of recent evidence
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721214/
https://www.ncbi.nlm.nih.gov/pubmed/33299954
http://dx.doi.org/10.1097/j.pbj.0000000000000105
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