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Drug-Induced Liver Injury Caused by “Khat,” an Herbal Stimulant

We describe a case of Catha edulis (Khat) drug-induced liver injury in a 28-year-old man from Yemen. The patient presented with jaundice, fatigue, and anorexia. Extensive workup, including liver biopsy, was performed. This is the first reported case in the United States without definite autoimmune h...

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Detalles Bibliográficos
Autores principales: Palacios Argueta, Pedro, Attar, Bashar, Sikavi, Cameron, Alagiozian-Angelova, Victoria, Mishra, Satya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721222/
https://www.ncbi.nlm.nih.gov/pubmed/33299901
http://dx.doi.org/10.14309/crj.0000000000000480
Descripción
Sumario:We describe a case of Catha edulis (Khat) drug-induced liver injury in a 28-year-old man from Yemen. The patient presented with jaundice, fatigue, and anorexia. Extensive workup, including liver biopsy, was performed. This is the first reported case in the United States without definite autoimmune hepatitis. Diagnosis requires high clinical suspicion and extensive workup. Increasing migration and differences in cultural practices lead to the need for an increased awareness of this type of cases, which is underreported.