Drug-Induced Liver Injury Caused by “Khat,” an Herbal Stimulant

We describe a case of Catha edulis (Khat) drug-induced liver injury in a 28-year-old man from Yemen. The patient presented with jaundice, fatigue, and anorexia. Extensive workup, including liver biopsy, was performed. This is the first reported case in the United States without definite autoimmune h...

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Autores principales: Palacios Argueta, Pedro, Attar, Bashar, Sikavi, Cameron, Alagiozian-Angelova, Victoria, Mishra, Satya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721222/
https://www.ncbi.nlm.nih.gov/pubmed/33299901
http://dx.doi.org/10.14309/crj.0000000000000480
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author Palacios Argueta, Pedro
Attar, Bashar
Sikavi, Cameron
Alagiozian-Angelova, Victoria
Mishra, Satya
author_facet Palacios Argueta, Pedro
Attar, Bashar
Sikavi, Cameron
Alagiozian-Angelova, Victoria
Mishra, Satya
author_sort Palacios Argueta, Pedro
collection PubMed
description We describe a case of Catha edulis (Khat) drug-induced liver injury in a 28-year-old man from Yemen. The patient presented with jaundice, fatigue, and anorexia. Extensive workup, including liver biopsy, was performed. This is the first reported case in the United States without definite autoimmune hepatitis. Diagnosis requires high clinical suspicion and extensive workup. Increasing migration and differences in cultural practices lead to the need for an increased awareness of this type of cases, which is underreported.
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spelling pubmed-77212222020-12-08 Drug-Induced Liver Injury Caused by “Khat,” an Herbal Stimulant Palacios Argueta, Pedro Attar, Bashar Sikavi, Cameron Alagiozian-Angelova, Victoria Mishra, Satya ACG Case Rep J Case Report We describe a case of Catha edulis (Khat) drug-induced liver injury in a 28-year-old man from Yemen. The patient presented with jaundice, fatigue, and anorexia. Extensive workup, including liver biopsy, was performed. This is the first reported case in the United States without definite autoimmune hepatitis. Diagnosis requires high clinical suspicion and extensive workup. Increasing migration and differences in cultural practices lead to the need for an increased awareness of this type of cases, which is underreported. Wolters Kluwer 2020-11-23 /pmc/articles/PMC7721222/ /pubmed/33299901 http://dx.doi.org/10.14309/crj.0000000000000480 Text en © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Palacios Argueta, Pedro
Attar, Bashar
Sikavi, Cameron
Alagiozian-Angelova, Victoria
Mishra, Satya
Drug-Induced Liver Injury Caused by “Khat,” an Herbal Stimulant
title Drug-Induced Liver Injury Caused by “Khat,” an Herbal Stimulant
title_full Drug-Induced Liver Injury Caused by “Khat,” an Herbal Stimulant
title_fullStr Drug-Induced Liver Injury Caused by “Khat,” an Herbal Stimulant
title_full_unstemmed Drug-Induced Liver Injury Caused by “Khat,” an Herbal Stimulant
title_short Drug-Induced Liver Injury Caused by “Khat,” an Herbal Stimulant
title_sort drug-induced liver injury caused by “khat,” an herbal stimulant
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721222/
https://www.ncbi.nlm.nih.gov/pubmed/33299901
http://dx.doi.org/10.14309/crj.0000000000000480
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